Patil Urjita, Yeli Mahantesh, Tapashetti Sharmila, Naik Balaram, Tilakchand Mahima
Department of Conservative Dentistry and Endodontics, SDM College of Dental Sciences and Hospital, Dharwad, Karnataka, India.
J Conserv Dent. 2019 Jan-Feb;22(1):48-53. doi: 10.4103/JCD.JCD_80_18.
The aim of the present study was to evaluate the effect of varying durations of intracanal medicament application used in regenerative endodontic treatment on the push out the bond strength of a novel cement-NeoMTA Plus.
A total of 60 extracted single-rooted maxillary anterior teeth were decoronated. Roots were instrumented uniformly until Peeso Reamer size #5 to simulate open apices. A total of 60 roots were then divided into four groups according to intracanal medicaments used ( = 15): Group 1: Triple antibiotic paste (TAP); Group 2: Double antibiotic paste (DAP); Group 3: Calcium hydroxide paste (CH); and Group 4 (control): No medicament. Samples were kept in saline solution for 2, 4, and 12 weeks, after which time five roots were selected randomly from each group, representing the samples of each time point. After removal of the medicaments, NeoMTA Plus was placed into 8 mm of the coronal third of the roots and samples were incubated. Roots were sectioned to obtain 2 discs per root ( = 10). A push-out test was used to measure the sealing efficacy of NeoMTA Plus. Data were analyzed using a one-way ANOVA followed by Tukey's pairwise comparisons.
CH, DAP, and TAP application resulted in significantly lower values of the push-out bond strength of NeoMTA Plus after 12 weeks compared to 2 weeks ( < 0.05). [Table: see text] No significant differences were found between the time points in the control group ( > 0.05). [Table: see text] DAP showed lowest push-out bond strength. [Table: see text].
CH, DAP, and TAP cause an alteration in dentinal surface properties leading to negative effect on bond strength of NeoMTA Plus. The effect is more evident in DAP and as treatment time is prolonged. The type and duration of medicament application have to be monitored to achieve a maximum therapeutic value as well as to avoid compromise on the coronal seal.
本研究旨在评估在再生牙髓治疗中使用不同时长的根管内药物对一种新型水门汀——NeoMTA Plus推出粘结强度的影响。
总共60颗拔除的上颌单根前牙被截冠。将牙根统一预备至Peeso扩孔钻5号以模拟根尖开放。然后根据所使用的根管内药物将60个牙根分为四组（每组n = 15）：第1组：三联抗生素糊剂（TAP）；第2组：双联抗生素糊剂（DAP）；第3组：氢氧化钙糊剂（CH）；第4组（对照组）：不使用药物。样本在盐溶液中保存2周、4周和12周，之后从每组中随机选取5个牙根，代表每个时间点的样本。去除药物后，将NeoMTA Plus置于牙根冠方三分之一的8 mm处并孵育样本。将牙根切片，每个牙根获得2个圆盘（每组n = 10）。采用推出试验测量NeoMTA Plus的封闭效果。数据采用单因素方差分析，随后进行Tukey两两比较。
与2周相比，12周后使用CH、DAP和TAP导致NeoMTA Plus的推出粘结强度值显著降低（P < 0.05）。[表：见正文]对照组各时间点之间未发现显著差异（P > 0.05）。[表：见正文]DAP显示出最低的推出粘结强度。[表：见正文]。
CH、DAP和TAP会导致牙本质表面性能改变，从而对NeoMTA Plus的粘结强度产生负面影响。这种影响在DAP中更明显，且随着治疗时间延长而更显著。必须监测药物应用的类型和时长，以实现最大治疗价值并避免冠部封闭受到影响。
