Hargreaves Kenneth M, Diogenes Anibal, Teixeira Fabricio B
Department of Endodontics, University of Texas Health Science Center at San Antonio, San Antonio, Texas.
Department of Endodontics, University of Texas Health Science Center at San Antonio, San Antonio, Texas.
J Endod. 2014 Apr;40(4 Suppl):S65-9. doi: 10.1016/j.joen.2014.01.023.
Regenerative endodontic procedures are rapidly gaining the attention of clinicians and investigators alike. However, it is often challenging to understand various regenerative studies and to interpret their results. The present review addresses this problem by focusing on recent strategies for developing standardized clinical protocols, understanding the full spectrum of clinical and translational research and its relationship to selection of proper outcome measures, as well as reviewing the fundamental role of paradigms in designing and interpreting regenerative studies.
再生牙髓治疗程序正迅速引起临床医生和研究人员的关注。然而，理解各种再生研究并解释其结果往往具有挑战性。本综述通过关注制定标准化临床方案的最新策略、理解临床和转化研究的全貌及其与选择适当结局指标的关系，以及回顾范式在设计和解释再生研究中的基本作用来解决这一问题。
