Organelle Biology and Biotechnology Research Group, Max Planck Institute of Molecular Plant Physiology, 14476 Potsdam-Golm, Germany.
Current affiliation: Institute of Plant Physiology, Martin-Luther-University Halle-Wittenberg, 06120 Halle, Germany; email:
Annu Rev Plant Biol. 2019 Apr 29;70:23-50. doi: 10.1146/annurev-arplant-050718-100412. Epub 2019 Mar 1.
Plant mitochondria play a major role during respiration by producing the ATP required for metabolism and growth. ATP is produced during oxidative phosphorylation (OXPHOS), a metabolic pathway coupling electron transfer with ADP phosphorylation via the formation and release of a proton gradient across the inner mitochondrial membrane. The OXPHOS system is composed of large, multiprotein complexes coordinating metal-containing cofactors for the transfer of electrons. In this review, we summarize the current state of knowledge about assembly of the OXPHOS complexes in land plants. We present the different steps involved in the formation of functional complexes and the regulatory mechanisms controlling the assembly pathways. Because several assembly steps have been found to be ancestral in plants-compared with those described in fungal and animal models-we discuss the evolutionary dynamics that lead to the conservation of ancestral pathways in land plant mitochondria.
植物线粒体在呼吸过程中起着重要作用，通过产生代谢和生长所需的 ATP。ATP 是在氧化磷酸化（OXPHOS）过程中产生的，这是一种代谢途径，通过在线粒体内膜两侧形成和释放质子梯度将电子传递与 ADP 磷酸化偶联。OXPHOS 系统由大型多蛋白复合物组成，协调含有金属辅因子的电子转移。在这篇综述中，我们总结了目前关于陆地植物 OXPHOS 复合物组装的知识状态。我们介绍了形成功能复合物的不同步骤和控制组装途径的调节机制。由于与真菌和动物模型中描述的相比，已经发现几个组装步骤在植物中是祖先的，因此我们讨论了导致祖先途径在陆地植物线粒体中保守的进化动态。
