Department of Food Engineering and Technology, Institute of Chemical Technology, Matunga, Mumbai, 400019, India.
Department of Food Engineering and Technology, Institute of Chemical Technology, Matunga, Mumbai, 400019, India.
Carbohydr Polym. 2019 May 1;211:124-132. doi: 10.1016/j.carbpol.2019.02.005. Epub 2019 Feb 4.
In this study, biogenic AgNPs were synthesize using Nigella sativa extract (NSE) with potential antioxidant activity. The transmission electron microscopy (TEM) image showed spherical AgNPs with biphasic nature and an average particle size 8 nm. AgNPs was then evaluated for their effect on sustained release and film-forming capacity of chitosan. Characterization of the films was done to analyze their physical, mechanical as well as antibacterial properties. The structural change in the films was indicated by FTIR spectra which showed the shift of characteristics peak and modification of the absorbance intensity. Scanning electron micrographs (SEM) showed an uneven distribution of AgNPs all over the CS polymer matrix. Moreover, the mechanical and barrier properties of CS/ Ag nanocomposite films were influenced by the intercalation of AgNPs. The tensile strength and elongation of the films were improved by 8.4-22.5% and 4.4-9.2%, whereas water vapor permeability reduced by 15.23% depending on the concentration of AgNPs. Further, the films showed a pH-dependent sustained release of AgNPs and Ag ions and significant antibacterial activity. Largely, the excellent antibacterial activity and biocompatibility mark CS-AgNPs composite films a promising material for packaging of food, pharmaceutical, and allied products.
在这项研究中，使用具有潜在抗氧化活性的黑种草提取物（NSE）合成了生物源 AgNPs。透射电子显微镜（TEM）图像显示出具有双相性质和平均粒径为 8nm 的球形 AgNPs。然后评估了 AgNPs 对壳聚糖的缓释和成膜能力的影响。对薄膜进行了表征，以分析其物理、机械和抗菌性能。FTIR 光谱显示特征峰的位移和吸光度强度的修饰表明了薄膜的结构变化。扫描电子显微镜（SEM）显示 AgNPs 不均匀地分布在 CS 聚合物基质中。此外，AgNPs 的插入影响了 CS/Ag 纳米复合材料薄膜的机械和阻隔性能。薄膜的拉伸强度和伸长率提高了 8.4-22.5%和 4.4-9.2%，而水蒸气透过率降低了 15.23%，这取决于 AgNPs 的浓度。此外，薄膜表现出 pH 依赖性的 AgNPs 和 Ag 离子缓释和显著的抗菌活性。总的来说，优异的抗菌活性和生物相容性使 CS-AgNPs 复合薄膜成为包装食品、制药和相关产品的有前途的材料。
