William S. Middleton Memorial Veterans Hospital, Addictive Disorders Treatment Program, 2500 Overlook Terrace, Madison, WI, 53705, USA.
Institute for Health Research and Policy, University of Illinois at Chicago, (MC 275), 544 Westside Research Office Bldg., 1747 West Roosevelt Road, Chicago, IL, 60608, USA.
Drug Alcohol Depend. 2019 Apr 1;197:149-157. doi: 10.1016/j.drugalcdep.2019.01.011. Epub 2019 Feb 16.
Smoking reduction treatment is a promising approach to increase abstinence amongst smokers initially unwilling to quit. However, little is known about which reduction treatment elements increase quit attempts and the uptake of cessation treatment amongst such smokers.
This study is a secondary analysis of a 4-factor randomized factorial experiment conducted amongst primary care patients (N = 517) presenting for regular healthcare visits in Southern Wisconsin who were unwilling to quit smoking but willing to cut down. We evaluated the main and interactive effects of Motivation-phase intervention components on whether participants: 1) made a quit attempt (intentional abstinence ≥24 h) by 6- and 26-weeks post-study enrollment and, 2) used cessation treatment. We also evaluated the relations of quit attempts with abstinence. The four intervention components evaluated were: 1) Nicotine Patch vs. None; 2) Nicotine Gum vs. None; 3) Motivational Interviewing (MI) vs. None; and 4) Behavioral Reduction Counseling (BR) vs. None. Intervention components were administered over 6 weeks, with an option to repeat treatment; participants could request cessation treatment at any point.
Nicotine gum significantly increased the likelihood of making a quit attempt by 6 weeks (23% vs. 15% without gum; p < .05). Conversely, nicotine patch reduced quit attempts when used with BR. Patch also discouraged use of cessation treatment (15.8% vs. 23% without patch; p < .05). Aided vs. unaided quit attempts produced abstinence in 42% vs. 10% of participants, respectively.
Nicotine gum is a promising Motivation-phase intervention that may spur quit attempts amongst smokers initially unwilling to quit.
减少吸烟量的治疗方法是一种很有前途的方法,可以增加最初不愿意戒烟的吸烟者的戒烟率。然而,对于哪些减少吸烟量的治疗方法能够增加此类吸烟者的戒烟尝试次数和接受戒烟治疗的比例,我们知之甚少。
本研究是在威斯康星州南部的初级保健患者(N=517)中进行的 4 因素随机析因实验的二次分析,这些患者在就诊时不愿意戒烟,但愿意减少吸烟量。我们评估了动机阶段干预措施的主要和交互作用对以下方面的影响:1)参与者在研究入组后 6 周和 26 周是否尝试戒烟(意图性戒烟≥24 小时);2)是否使用戒烟治疗。我们还评估了戒烟尝试与戒烟的关系。评估的四个干预措施包括:1)尼古丁贴片与无贴片;2)尼古丁口香糖与无口香糖;3)动机访谈(MI)与无 MI;4)行为减少咨询(BR)与无 BR。干预措施在 6 周内实施,并可选择重复治疗;参与者可随时要求接受戒烟治疗。
尼古丁口香糖显著增加了 6 周内戒烟尝试的可能性(使用口香糖者为 23%,未使用者为 15%;p<0.05)。相反,BR 联合尼古丁贴片会降低戒烟尝试率。贴片还会阻止使用戒烟治疗(使用贴片者为 15.8%,未使用者为 23%;p<0.05)。辅助戒烟尝试和未辅助戒烟尝试分别使 42%和 10%的参与者实现了戒烟。
尼古丁口香糖是一种很有前途的动机阶段干预措施,它可能会促使最初不愿意戒烟的吸烟者尝试戒烟。