Wyatt S E, Lafuente P, Ter Haar G, Packer R M A, Smith H, De Decker S
Department of Veterinary Clinical Science and Services, Royal Veterinary College, University of London, Hawkshead lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, England, United Kingdom.
Department of Veterinary Clinical Science and Services, Royal Veterinary College, University of London, Hawkshead lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, England, United Kingdom.
Vet J. 2019 Feb;244:45-50. doi: 10.1016/j.tvjl.2018.12.008. Epub 2018 Dec 12.
The study objective was to compare temporal-spatial and kinetic gait variables in neurologically normal French bulldogs with and without vertebral kyphosis. French bulldogs presented to a dedicated brachycephalic clinic were prospectively enrolled. All dogs underwent general physical, orthopaedic, and neurological examination prior to study inclusion. The presence of vertebral kyphosis was evaluated by computed tomography and kyphosis was defined as a Cobb angle exceeding 10°. Gait variables were collected using a pressure-sensitive GAITRite walkway with GAITFour software and included measurement of total pressure index (TPI) defined as the sum of peak pressure values recorded from each activated sensor by a paw during mat contact. Fifteen French bulldogs with (n=8) and without kyphosis (n=7) were included. Cobb angle in kyphotic dogs ranged from 14.9° to 39.5°. Univariate analyses were initially performed to examine the association between kyphosis and 16 gait variables. When those variables found to be associated (P<0.2) were taken forward into multivariate generalised linear mixed models (accounting for dog, velocity and side), kyphosis had a significant effect upon TPI of the forelimbs and TPI symmetry ratio (P<0.05); however, the size of these effects was small. Although vertebral kyphosis is rarely associated with neurological deficits, it was associated with subtle alterations in kinetic gait variables (TPI forelimbs and TPI symmetry ratio). Further studies are needed to evaluate the clinical importance of altered gait variables in French bulldogs with kyphosis.
本研究的目的是比较患有和未患有脊柱后凸的神经功能正常的法国斗牛犬的时空步态变量和动力学步态变量。前瞻性纳入了前往一家专门的短头犬诊所就诊的法国斗牛犬。所有犬只在纳入研究前均接受了全面的体格、骨科和神经学检查。通过计算机断层扫描评估脊柱后凸的存在，后凸定义为Cobb角超过10°。使用带有GAITFour软件的压敏GAITRite步道收集步态变量，包括测量总压力指数（TPI），其定义为爪子在垫子接触期间从每个激活传感器记录的峰值压力值之和。纳入了15只患有（n = 8）和未患有后凸（n = 7）的法国斗牛犬。患有后凸的犬只的Cobb角范围为14.9°至39.5°。最初进行单变量分析以检查后凸与16个步态变量之间的关联。当发现那些相关的变量（P < 0.2）被纳入多变量广义线性混合模型（考虑犬只、速度和侧别）时，后凸对前肢的TPI和TPI对称比有显著影响（P < 0.05）；然而，这些影响的大小较小。虽然脊柱后凸很少与神经功能缺损相关，但它与动力学步态变量（前肢TPI和TPI对称比）的细微改变有关。需要进一步研究来评估后凸的法国斗牛犬步态变量改变的临床重要性。
