Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India.
Post Graduate Institute of Dental Sciences, Rohtak, Haryana, India.
J Endod. 2019 Apr;45(4):357-363. doi: 10.1016/j.joen.2019.01.003. Epub 2019 Mar 1.
The aim of this study was to evaluate the effect of 2 different concentrations of sodium hypochlorite on healing and postoperative pain after primary endodontic treatment.
One hundred mandibular molars with pulp necrosis and chronic apical periodontitis were randomly assigned to 2 treatment groups: high-concentration (HC) 5% sodium hypochlorite and low-concentration (LC) 1% sodium hypochlorite. Root canal treatment was performed using a standardized protocol. Canals were prepared using equal volumes of respective irrigants after each instrument change. After chemomechanical preparation, the final flush was performed with 5 mL 17% EDTA solution followed by 5 mL 5% or 1% sodium hypochlorite depending on the group. All patients were asked to record the degree of pain on a visual analog scale every 24 hours for 1 week. At the second visit, canals were obturated, and the teeth were restored permanently. Clinical and radiographic evaluations were performed every 3 months for 12 months. The data collected were statistically analyzed.
Eighty-six teeth were available for evaluation at the 1-year follow-up. The overall healing rate observed was 76.7%. Greater healing was observed in the HC (81.4%) group compared with the LC group (72.1%), but the difference was not statistically significant (P > .05). No significant differences in pain incidence and pain scores were found between the 2 groups (P >.05), with lower values reported in the LC group.
The use of LC or HC sodium hypochlorite did not result in a significant difference in the clinical outcome.
本研究旨在评估两种不同浓度次氯酸钠对上primary 牙髓治疗后愈合和术后疼痛的影响。
100 颗下颌磨牙因牙髓坏死和慢性根尖周炎被随机分配到两个治疗组：高浓度（HC）5%次氯酸钠和低浓度（LC）1%次氯酸钠。采用标准化方案进行根管治疗。每次器械更换后，用等量的相应冲洗液冲洗根管。化学机械预备后，用 5mL 17%EDTA 溶液进行最终冲洗，然后根据组别用 5mL 5%或 1%次氯酸钠冲洗。所有患者均被要求在 1 周内每 24 小时记录疼痛程度的视觉模拟评分。第二次就诊时，用 5mL 17%EDTA 溶液进行最终冲洗，然后根据组别用 5mL 5%或 1%次氯酸钠冲洗。所有患者均被要求在 1 周内每 24 小时记录疼痛程度的视觉模拟评分。第二次就诊时，用 5mL 17%EDTA 溶液进行最终冲洗，然后根据组别用 5mL 5%或 1%次氯酸钠冲洗。所有患者均被要求在 1 周内每 24 小时记录疼痛程度的视觉模拟评分。第二次就诊时，用 5mL 17%EDTA 溶液进行最终冲洗，然后根据组别用 5mL 5%或 1%次氯酸钠冲洗。所有患者均被要求在 1 周内每 24 小时记录疼痛程度的视觉模拟评分。第二次就诊时， canals 被 obturated，牙齿被永久修复。在 12 个月内，每 3 个月进行一次临床和影像学评估。收集的数据进行了统计学分析。
在 1 年的随访中，有 86 颗牙齿可供评估。观察到的总体愈合率为 76.7%。HC（81.4%）组的愈合率高于 LC 组（72.1%），但差异无统计学意义（P>.05）。两组间疼痛发生率和疼痛评分无显著差异（P>.05），LC 组疼痛评分较低。
使用 LC 或 HC 次氯酸钠对临床结果没有显著影响。
