Lago Bruna Tozzati, Cecchin Doglas, Lenz Ulysses, Lago Carlo Theodoro Raymundi, Farina Ana Paula, Souza Matheus Albino, de Carli João Paulo, Bello Yuri Dal
Postgraduate Student, Dental School of Universidade de Passo Fundo, Passo Fundo, RS, Brazil.
Department of Restorative Dentistry, Dental School of Universidade de Passo Fundo, Passo Fundo, RS, Brazil.
J Clin Exp Dent. 2025 Apr 1;17(4):e432-e439. doi: 10.4317/jced.62446. eCollection 2025 Apr.
The aim of this study was to evaluate pain and analgesic intake after endodontic treatment using glycolic acid (GA) or ethylenediaminetetraacetic acid (EDTA) as the final irrigating solution.
One hundred fifty patients were randomly assigned to two groups for smear layer removal: 17% GA or 17% EDTA. Postoperative pain was assessed at 24, 48 hours and 7 days. The need for analgesic intake was recorded. Descriptive analysis was performed to assess demographics (Student t, Chi-square and Fisher tests) and study outcomes (Mann Whitney, Friedman and Nemenyi) (<0,05).
Postoperative pain occurred in 52% of the cases. In the 24-hour period, GA had a significantly lower pain score (<0.05). There was no statistical difference between the groups regarding the use of analgesic pills.
GA is associated with less postoperative pain at 24 hours compared to EDTA. No statistically significant difference was observed at 48 hours and 7 days. Postoperative pain, randomized controlled trial, ethylenediaminetetraacetic acid, glycolic acid, analgesic.
本研究的目的是评估使用乙醇酸（GA）或乙二胺四乙酸（EDTA）作为最终冲洗液进行根管治疗后的疼痛和镇痛药物摄入量。
150例患者被随机分为两组以去除玷污层：17%乙醇酸组或17%乙二胺四乙酸组。在术后24小时、48小时和7天评估术后疼痛情况。记录镇痛药物的使用需求。进行描述性分析以评估人口统计学特征（学生t检验、卡方检验和费舍尔检验）和研究结果（曼-惠特尼检验、弗里德曼检验和内梅尼检验）（P<0.05）。
52%的病例出现术后疼痛。在术后24小时内，乙醇酸组的疼痛评分显著更低（P<0.05）。两组在镇痛药物使用方面无统计学差异。
与乙二胺四乙酸相比，乙醇酸在术后24小时引起的疼痛更少。在48小时和7天时未观察到统计学显著差异。术后疼痛、随机对照试验、乙二胺四乙酸、乙醇酸、镇痛药
