Oliveira-Filho Eduardo Cyrino, Muniz Daphne Heloísa de Freitas, Carvalho Esther Lima de, Cáceres-Velez Paolin Rocio, Fascineli Maria Luiza, Azevedo Ricardo Bentes, Grisolia Cesar Koppe
Embrapa Cerrados, Rodovia BR 020, Km 18, Planaltina, DF 73301-970, Brazil.
Centro Universitário de Brasília (UniCEUB), Faculdade de Ciências da Educação e Saúde (FACES), Brasília, DF 70790-075, Brazil.
Toxics. 2019 Mar 1;7(1):12. doi: 10.3390/toxics7010012.
Silver nanoparticles (AgNPs) are used intensively in medical and industrial applications. Environmental concerns have arisen from the potential release of this material into aquatic ecosystems. The aims of this research were to evaluate the potential accumulation of silver in the whole body of organisms and analyze the effects of AgNPs on the survival and reproduction of the snail . Results show slow acute toxicity with a 10-day LC of 18.57 mg/L and an effective decrease in the eggs and egg clutches per organism exposed to tested concentrations. Based on these data, the No Observed Effect Concentration (NOEC) observed was <1 mg/L for snail reproduction. For silver accumulation, we observed that uptake was faster than elimination, which was very slow and still incomplete 35 days after the end of the experiment. However, the observed accumulation was not connected with a concentration/response relationship, since the amount of silver was not equivalent to a higher reproductive effect. The data observed show that AgNPs are toxic to , and suggest that the snail has internal mechanisms to combat the presence of Ag in its body, ensuring survival and reduced reproduction and showing that the species seems to be a potential indicator for Ag presence in contaminated aquatic ecosystems.
银纳米颗粒（AgNPs）在医学和工业应用中被广泛使用。人们对这种材料可能释放到水生生态系统中产生了环境方面的担忧。本研究的目的是评估银在生物体全身的潜在积累情况，并分析AgNPs对蜗牛生存和繁殖的影响。结果显示出缓慢的急性毒性，10天半数致死浓度为18.57毫克/升，并且暴露于测试浓度下的每个生物体的卵和卵块数量有效减少。基于这些数据，观察到的蜗牛繁殖的无观察效应浓度（NOEC）<1毫克/升。对于银的积累，我们观察到摄取速度比消除速度快，消除速度非常缓慢，在实验结束35天后仍未完全消除。然而，观察到的积累与浓度/反应关系无关，因为银的量并不等同于更高的繁殖效应。观察到的数据表明AgNPs对[此处原文缺失相关内容]有毒，并表明蜗牛具有内部机制来对抗体内银的存在，确保生存并减少繁殖，这表明该物种似乎是受污染水生生态系统中银存在的潜在指示生物。
