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致病性真菌ATCC 36193的基因组测序草图鉴定出参与苝醌类色素产生的新型聚酮合酶基因的候选基因。

Draft Genome Sequencing of the Pathogenic Fungus ATCC 36193 Identifies Candidates of Novel Polyketide Synthase Genes Involved in Perylenequinone-Group Pigment Production.

作者信息

Kang Yu-Na, So Kum-Kang, Kim Do-Wan, Kim Dae-Hyuk, Lee Tae-Ho

机构信息

Genomics Division, National Institute of Agricultural Science, Jeonju, Korea.

Department of Molecular Biology, Chonbuk National University, Jeonju, Korea.

出版信息

Evol Bioinform Online. 2019 Feb 26;15:1176934319831306. doi: 10.1177/1176934319831306. eCollection 2019.

DOI:10.1177/1176934319831306
PMID:30833809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6393816/
Abstract

, which causes purple eyespot disease, has been focused on as a source of phleichrome from the perylenequinone group of pigments. Although this agent is important in photodynamic therapy, there are no genome sequences for the species. Here, we sequenced the genome of and reported the draft sequence. The total length of the draft genome was approximately 31.8 Mb, and 9571 genes were predicted. Phylogenetic analysis showed that sp., and were closely related, and this result corresponded to the taxonomic data. In addition to the draft genome sequence, we report four candidates of new polyketide synthase (PKS) genes, involved in the production of perylenequinone-group pigments.

摘要

引起紫斑病的[具体物种名称未给出]，作为苝醌类色素中苝醌色素的来源已受到关注。尽管该病原体在光动力疗法中很重要，但该物种尚无基因组序列。在此，我们对[具体物种名称未给出]的基因组进行了测序并报告了草图序列。草图基因组的总长度约为31.8 Mb，预测有9571个基因。系统发育分析表明[具体物种名称未给出]与[相关物种名称未给出]密切相关，这一结果与分类学数据相符。除了草图基因组序列外，我们还报告了四个参与苝醌类色素生产的新聚酮合酶（PKS）基因候选序列。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f54/6393816/c193caf11881/10.1177_1176934319831306-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f54/6393816/c193caf11881/10.1177_1176934319831306-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f54/6393816/c193caf11881/10.1177_1176934319831306-fig1.jpg

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