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孕期癌症:肿瘤学家概述

Cancer During Pregnancy: The Oncologist Overview.

作者信息

Hepner Adriana, Negrini Daniel, Hase Eliane Azeka, Exman Pedro, Testa Laura, Trinconi Angela F, Filassi Jose Roberto, Francisco Rossana Pulcineli Vieira, Zugaib Marcelo, O'Connor Tracey L, Martin Michael Gary

机构信息

Medical Oncology Service, Instituto do Cancer do Estado de Sao Paulo, Universidade de Sao Paulo, Sao Paulo, Brazil.

Department of Obstetrics and Gynecology, University of Sao Paulo Medical School, Sao Paulo, Brazil.

出版信息

World J Oncol. 2019 Feb;10(1):28-34. doi: 10.14740/wjon1177. Epub 2019 Feb 26.

Abstract

Although a rare and challenging condition, cancer during pregnancy should promptly be identified and treated. Not only standards of care guidelines for the underlying disease are taken into account, but also fetal safety might be weighted for clinical decisions. Frequent lack of experience and knowledge about this condition could lead to late diagnosis, imprecise management, suboptimal treatment and fetal and maternal harm. Therefore, this review aims to summarize the current evidence regarding the epidemiology, clinical presentation, diagnostic workup, staging and treatment, including novel treatment modalities for patients diagnosed with cancer during pregnancy.

摘要

尽管孕期癌症是一种罕见且具有挑战性的病症,但仍应及时予以识别和治疗。临床决策不仅要考虑基础疾病的护理标准指南,还需权衡胎儿安全。对此病症经验和知识的频繁欠缺可能导致诊断延迟、管理不精确、治疗欠佳以及对胎儿和母亲造成伤害。因此,本综述旨在总结有关孕期癌症患者的流行病学、临床表现、诊断检查、分期及治疗,包括新型治疗方式的现有证据。

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本文引用的文献

1
Pembrolizumab is effective for drug-resistant gestational trophoblastic neoplasia.
Lancet. 2017 Nov 25;390(10110):2343-2345. doi: 10.1016/S0140-6736(17)32894-5.
2
Committee Opinion No. 723: Guidelines for Diagnostic Imaging During Pregnancy and Lactation.
Obstet Gynecol. 2017 Oct;130(4):e210-e216. doi: 10.1097/AOG.0000000000002355.
3
Immune checkpoint inhibitors in challenging populations.
Cancer. 2017 Jun 1;123(11):1904-1911. doi: 10.1002/cncr.30642. Epub 2017 Feb 27.
4
Anaesthesia for non-obstetric surgery during pregnancy.
Indian J Anaesth. 2016 Apr;60(4):234-41. doi: 10.4103/0019-5049.179445.
5
An Evaluation of the Impact of PD-1 Pathway Blockade on Reproductive Safety of Therapeutic PD-1 Inhibitors.
Birth Defects Res B Dev Reprod Toxicol. 2016 Apr;107(2):108-19. doi: 10.1002/bdrb.21176. Epub 2016 Apr 7.
6
Difficulties with diagnosis of malignancies in pregnancy.
Best Pract Res Clin Obstet Gynaecol. 2016 May;33:19-32. doi: 10.1016/j.bpobgyn.2015.10.005. Epub 2015 Oct 19.
7
Cancer during pregnancy and the postpartum period: A population-based study.
Cancer. 2015 Jun 15;121(12):2072-7. doi: 10.1002/cncr.29325. Epub 2015 Mar 3.
8
Tyrosine kinase inhibitors and pregnancy.
Mediterr J Hematol Infect Dis. 2014 Apr 7;6(1):e2014028. doi: 10.4084/MJHID.2014.028. eCollection 2014.
10
Cancer, pregnancy and fertility: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.
Ann Oncol. 2013 Oct;24 Suppl 6:vi160-70. doi: 10.1093/annonc/mdt199. Epub 2013 Jun 27.

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