Hepner Adriana, Negrini Daniel, Hase Eliane Azeka, Exman Pedro, Testa Laura, Trinconi Angela F, Filassi Jose Roberto, Francisco Rossana Pulcineli Vieira, Zugaib Marcelo, O'Connor Tracey L, Martin Michael Gary
Medical Oncology Service, Instituto do Cancer do Estado de Sao Paulo, Universidade de Sao Paulo, Sao Paulo, Brazil.
Department of Obstetrics and Gynecology, University of Sao Paulo Medical School, Sao Paulo, Brazil.
World J Oncol. 2019 Feb;10(1):28-34. doi: 10.14740/wjon1177. Epub 2019 Feb 26.
Although a rare and challenging condition, cancer during pregnancy should promptly be identified and treated. Not only standards of care guidelines for the underlying disease are taken into account, but also fetal safety might be weighted for clinical decisions. Frequent lack of experience and knowledge about this condition could lead to late diagnosis, imprecise management, suboptimal treatment and fetal and maternal harm. Therefore, this review aims to summarize the current evidence regarding the epidemiology, clinical presentation, diagnostic workup, staging and treatment, including novel treatment modalities for patients diagnosed with cancer during pregnancy.
尽管孕期癌症是一种罕见且具有挑战性的病症,但仍应及时予以识别和治疗。临床决策不仅要考虑基础疾病的护理标准指南,还需权衡胎儿安全。对此病症经验和知识的频繁欠缺可能导致诊断延迟、管理不精确、治疗欠佳以及对胎儿和母亲造成伤害。因此,本综述旨在总结有关孕期癌症患者的流行病学、临床表现、诊断检查、分期及治疗,包括新型治疗方式的现有证据。