一例在治疗向心性肥厚过程中通过新型心踝血管指数展示心血管相互作用的病例

Shimizu Kazuhiro, Tabata Tsuyoshi, Kiyokawa Hajime, Morinaga Yukihiro, Sato Shuji, Mikamo Hiroshi, Nakagami Takahiro, Iiduka Takuo, Shirai Kohji, Noro Mahito

Department of Internal Medicine, Toho University Sakura Medical Center, Chiba, Japan.

Department of Clinical Physiology, Toho University Sakura Medical Center, Chiba, Japan.

Cardiol Res. 2019 Feb;10(1):54-58. doi: 10.14740/cr812. Epub 2019 Feb 24.

A 42-year-old hypertensive woman came to our hospital suffering from shortness of breath. Her left ventricular mass index (LVMI) was increased, and a new arterial stiffness index, cardio-ankle vascular index (CAVI), was also elevated. By treating hypertension (HT), diabetes mellitus (DM) and obstructive sleep apnea (OSA), her left ventricular concentric hypertrophy was improved, accompanying with a decrease in CAVI. These observations suggested that arterial stiffness monitored with CAVI might be involved in cardiac hypertrophy. This cardio-vascular interaction could be demonstrated at the first time by monitoring CAVI, which is not affected by blood pressure (BP) at measuring time.

一名42岁的高血压女性因呼吸急促前来我院就诊。她的左心室质量指数（LVMI）升高，一种新的动脉僵硬度指数——心踝血管指数（CAVI）也升高。通过治疗高血压（HT）、糖尿病（DM）和阻塞性睡眠呼吸暂停（OSA），她的左心室向心性肥厚得到改善，同时CAVI降低。这些观察结果表明，用CAVI监测的动脉僵硬度可能与心脏肥厚有关。通过监测CAVI首次证明了这种心血管相互作用，CAVI在测量时不受血压（BP）影响。