[人类和黑猩猩中α-Fuc to1p的定位以及非洲绿猴中其与4号染色体的关系]
[Assignment of alpha-Fuc to1p in man and the chimpanzee and to chromosome 4 in the African green monkey].
作者信息
Van Cong N, Weil D, Finaz C, Rebourcet R, Cochet C, de Grouchy J, Frézal J
出版信息
Ann Genet. 1978 Mar;21(1):41-6.
Analysis of cellular hybrids confirms the assignment of alpha-L-fucosidase (alpha-FUC) to 1p in man. Discordant results are in favour of the following gene order: 1pter (ENO-1, alpha-FUC,AK2) PGM1 centromere Pep-C but give no information on the relative positions of ENO-1,alpha-FUC, and AK2. The assignments of alpha-FUC to chromosome 1 in the chimpanzee and to chromosome 4 in the African green monkey are demonstrated (chromosome nomenclature by Finaz et al, 1976). These results confirm the homology of chromosome 4 of the African green monkey and 1p of man and the chimpanzee.
细胞杂交体分析证实了人类α-L-岩藻糖苷酶（α-FUC）定位于1p。不一致的结果支持以下基因顺序：1pter（烯醇化酶-1、α-FUC、腺苷酸激酶2）、磷酸葡萄糖变位酶1、着丝粒、肽酶C，但未提供烯醇化酶-1、α-FUC和腺苷酸激酶2相对位置的信息。已证明黑猩猩的α-FUC定位于1号染色体，非洲绿猴的α-FUC定位于4号染色体（采用Finaz等人1976年的染色体命名法）。这些结果证实了非洲绿猴4号染色体与人类和黑猩猩1p的同源性。
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