a Department of Psychiatry and Addiction , University of Montreal , Montreal , Canada.
b Department of Psychology , University of Exeter , Exeter , United Kingdom.
Stress. 2019 May;22(3):321-331. doi: 10.1080/10253890.2019.1579793. Epub 2019 Mar 5.
Stigma may strain the heart health of lesbian, gay, and bisexual (LGB) individuals. To date, however, LGB-related differences in cardiovascular diagnosis, risk factors, and basal biomarkers are inconsistently reported. Using a laboratory-based stress paradigm, the current study assessed whether cardiovascular stress reactivity differs as a function of sexual orientation and disclosure status ("coming out") in a sample of healthy young LGB and heterosexual adults. Eighty-seven participants aged 18-45 (M = 24.61 ± 0.61 SE) identifying as LGB and heterosexual (47%) were exposed to the Trier Social Stress Test, a well-validated laboratory stressor involving public speaking and mental arithmetic. Throughout a two-hour session, ambulatory recordings for heart rate and blood pressure were collected. Self-report questionnaires were also administered to assess psychosocial and demographic variables. Gay/bisexual men showed higher heart rate and lesbian/bisexual women showed marginally higher mean arterial blood pressure in response to a stressor, compared to sex- and age-matched heterosexuals. No significant differences emerged when comparing LGB individuals who had completely disclosed and those that had not completely disclosed their sexual orientation to family and friends. Compared to heterosexuals, heart rate is higher among gay/bisexual men and blood pressure is marginally higher among lesbian/bisexual women when exposed to a laboratory-based stressor. These preliminary findings contribute to small literature on sexual orientation differences in stress reactive biomarkers that requires further exploration. Lay abstract In response to stress exposure in a laboratory, gay/bisexual men showed higher heart rate than heterosexual men. By contrast, lesbian/bisexual showed a non-significant tendency towards higher blood pressure than heterosexual women. These preliminary findings suggest that the heart health of LGB individuals might be strained by stigma exposure.
污名可能会影响同性恋、双性恋和异性恋（LGB）个体的心脏健康。然而，迄今为止，LGB 相关的心血管诊断、风险因素和基础生物标志物的差异报告不一致。本研究使用基于实验室的应激范式，评估了在健康的年轻 LGB 和异性恋成年人样本中，性取向和披露状况（“出柜”）是否会影响心血管应激反应。87 名年龄在 18-45 岁之间的参与者（M = 24.61 ± 0.61 SE），自我认同为 LGB 和异性恋（47%），他们接受了特里尔社会应激测试，这是一种经过充分验证的实验室应激源，涉及公开演讲和心算。在两个小时的过程中，连续记录心率和血压。还进行了自我报告问卷，以评估心理社会和人口统计学变量。与性别和年龄匹配的异性恋者相比，男同性恋/双性恋者在面对应激源时的心率更高，女同性恋/双性恋者的平均动脉血压略高。当比较向家人和朋友完全披露和未完全披露性取向的 LGB 个体时，没有出现显著差异。与异性恋者相比，暴露于基于实验室的应激源时，男同性恋/双性恋者的心率更高，女同性恋/双性恋者的血压略高。这些初步发现为需要进一步探索的关于应激反应生物标志物中性取向差异的少量文献做出了贡献。
非专业人士译文
污名可能会影响同性恋、双性恋和异性恋（LGB）个体的心脏健康。然而，迄今为止，LGB 相关的心血管诊断、风险因素和基础生物标志物的差异报告不一致。本研究使用基于实验室的应激范式，评估了在健康的年轻 LGB 和异性恋成年人样本中，性取向和披露状况（“出柜”）是否会影响心血管应激反应。87 名年龄在 18-45 岁之间的参与者（M = 24.61 ± 0.61 SE），自我认同为 LGB 和异性恋（47%），他们接受了特里尔社会应激测试，这是一种经过充分验证的实验室应激源，涉及公开演讲和心算。在两个小时的过程中，连续记录心率和血压。还进行了自我报告问卷，以评估心理社会和人口统计学变量。与性别和年龄匹配的异性恋者相比，男同性恋/双性恋者在面对应激源时的心率更高，女同性恋/双性恋者的平均动脉血压略高。当比较向家人和朋友完全披露和未完全披露性取向的 LGB 个体时，没有出现显著差异。与异性恋者相比，暴露于基于实验室的应激源时，男同性恋/双性恋者的心率更高，女同性恋/双性恋者的血压略高。这些初步发现为需要进一步探索的关于应激反应生物标志物中性取向差异的少量文献做出了贡献。
