Kjaersgaard-Andersen P, Schmidt S A
Acta Orthop Scand. 1986 Feb;57(1):12-4. doi: 10.3109/17453678608993206.
Twelve patients at risk of developing postoperative para-articular ossifications were treated with indomethacin. Ossification after previous total hip arthroplasty was excised in eight patients. Four patients had ossification in the opposite hip after previous arthroplasty. Five patients in whom ectopic ossification was excised developed recurrences of lesser degree than the primary ossifications. One patient with the condition in the opposite hip developed ossification. No patients complained of stiffness in the hip and all had markedly increased hip motion. Indomethacin seems to be valuable as prophylaxis in patients at risk of developing ectopic ossification and as a supplement to secondary excision.
12名有发生术后关节周围骨化风险的患者接受了吲哚美辛治疗。8例患者切除了先前全髋关节置换术后的骨化组织。4例患者在先前关节置换术后对侧髋关节出现骨化。5例切除异位骨化的患者出现了程度较轻的复发，比原发性骨化程度轻。1例对侧髋关节有此病症的患者出现了骨化。没有患者抱怨髋关节僵硬，所有患者的髋关节活动度均明显增加。吲哚美辛似乎作为预防异位骨化风险患者的药物以及作为二次切除的补充是有价值的。
