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具有温度记忆特性的水凝胶心脏模型,用于手术模拟。

Hydrogel Heart Model with Temperature Memory Properties for Surgical Simulation.

机构信息

Department of Micro-Nano Mechanical Science and Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8601, Japan.

出版信息

Sensors (Basel). 2019 Mar 4;19(5):1102. doi: 10.3390/s19051102.

DOI:10.3390/s19051102
PMID:30836715
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6427373/
Abstract

The continual development of surgical technology has led to a demand for surgical simulators for evaluating and improving the surgical technique of surgeons. To meet these needs, simulators must incorporate a sensing function into the organ model for evaluating the surgical techniques. However, it is difficult to incorporate a temperature sensor into the conventional cardiac training model. In this study, we propose a heart model for surgical training of cardiac catheter ablation made from hydrogel, which has temperature memory properties. The heart model consists of a photo-crosslinkable hydrogel mixed with an irreversible temperature indicator that exhibits a color change from magenta to colorless at 55 °C. The Young's modulus, electrical resistivity, thermal conductivity, and specific heat capacity of the hydrogel material were evaluated and compared with those of human heart. Furthermore, temperature calibration based on the color of the hydrogel material confirmed that the temperature measurement accuracy of the material is ± 0.18 °C (at 56 °C). A heart model for catheter ablation was fabricated using the hydrogel material and a molding method, and the color change due to temperature change was evaluated.

摘要

外科技术的不断发展导致了对手术模拟器的需求,以评估和提高外科医生的手术技术。为了满足这些需求,模拟器必须在器官模型中纳入传感功能,以评估手术技术。然而,将温度传感器纳入传统的心脏训练模型是很困难的。在本研究中,我们提出了一种由水凝胶制成的用于心脏导管消融手术训练的心脏模型,该水凝胶具有温度记忆特性。心脏模型由光交联水凝胶和不可逆温度指示剂组成,当温度达到 55°C 时,颜色从洋红色变为无色。评估了水凝胶材料的杨氏模量、电阻率、热导率和比热容,并与人体心脏的相应值进行了比较。此外,基于水凝胶材料颜色的温度校准证实,材料的温度测量精度为±0.18°C(在 56°C 时)。使用水凝胶材料和成型方法制造了用于导管消融的心脏模型,并评估了由于温度变化引起的颜色变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/1930cd595822/sensors-19-01102-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/8e21cd92fbed/sensors-19-01102-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/f7a3d370eead/sensors-19-01102-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/9d8410289193/sensors-19-01102-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/0839b8536bd1/sensors-19-01102-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/1c684fe63d55/sensors-19-01102-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/a26e2b467d1f/sensors-19-01102-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/1b17a1cd61e3/sensors-19-01102-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/5685d9e7427d/sensors-19-01102-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/1930cd595822/sensors-19-01102-g009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/8e21cd92fbed/sensors-19-01102-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/f7a3d370eead/sensors-19-01102-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/9d8410289193/sensors-19-01102-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/0839b8536bd1/sensors-19-01102-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/1c684fe63d55/sensors-19-01102-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/a26e2b467d1f/sensors-19-01102-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/1b17a1cd61e3/sensors-19-01102-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/5685d9e7427d/sensors-19-01102-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01d8/6427373/1930cd595822/sensors-19-01102-g009.jpg

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