口服乙醇治疗乙二醇中毒
Treatment of Ethylene Glycol Poisoning with Oral Ethyl Alcohol.
作者信息
Achappa B, Madi D, Kanchan T, Kishanlal N K
机构信息
Associate Professor, Department of Internal Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, India.
Associate Professor, Department of Forensic Medicine & Toxicology, All India Institute of Medical Sciences, Jodhpur, India.
出版信息
Case Rep Med. 2019 Jan 30;2019:7985917. doi: 10.1155/2019/7985917. eCollection 2019.
Ethylene glycol poisoning is not uncommon in India. The ill effects are primarily caused by its toxic metabolites: glycolic acid and oxalic acid. A 70-year-old female presented to our hospital with ataxia after ingestion of ethylene glycol. The reported case describes the management of ethylene glycol poisoning using oral ethyl alcohol as an alternative to the recommended intravenous ethyl alcohol and fomepizole that are not available for use in India. The need for high degree of clinical suspicion, targeted investigations, and early instigation of treatment is of prime importance in cases of ethylene glycol poisoning as it can lead to long-term complications or even death.
乙二醇中毒在印度并不罕见。其不良影响主要由其有毒代谢产物：乙醇酸和草酸引起。一名70岁女性在摄入乙二醇后因共济失调前来我院就诊。该报告病例描述了使用口服乙醇治疗乙二醇中毒的方法，以此替代在印度无法使用的推荐静脉注射乙醇和甲吡唑。对于乙二醇中毒病例，高度的临床怀疑、针对性检查以及早期启动治疗至关重要，因为它可能导致长期并发症甚至死亡。
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