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A bolt from the blue: Lightning injuries.晴天霹雳:雷击伤
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J Med Life. 2014;7 Spec No. 3(Spec Iss 3):81-6.
3
Ethylene glycol poisoning: a rare but life-threatening cause of metabolic acidosis-a single-centre experience.乙二醇中毒:代谢性酸中毒的一种罕见但危及生命的病因——单中心经验
Clin Kidney J. 2012 Apr;5(2):120-3. doi: 10.1093/ckj/sfs009.
4
Ethylene glycol or methanol intoxication: which antidote should be used, fomepizole or ethanol?乙二醇或甲醇中毒:应使用哪种解毒剂,甲吡唑还是乙醇?
Neth J Med. 2014 Feb;72(2):73-9.
5
Librium for bed 1, a bottle of scotch for bed 2.给1号床用利眠宁,给2号床用一瓶苏格兰威士忌。
BMJ Case Rep. 2014 Mar 11;2014:bcr2013202809. doi: 10.1136/bcr-2013-202809.
6
Massive ethylene glycol ingestion treated with fomepizole alone-a viable therapeutic option.单独使用甲吡唑治疗大量乙二醇摄入——一种可行的治疗选择。
J Med Toxicol. 2010 Jun;6(2):131-4. doi: 10.1007/s13181-010-0061-2.
7
Ethylene glycol ingestion treated only with fomepizole.仅用甲吡唑治疗乙二醇摄入。
J Med Toxicol. 2007 Sep;3(3):125-8. doi: 10.1007/BF03160922.
8
Treatment of ethylene glycol poisoning.乙二醇中毒的治疗。
Am Fam Physician. 2002 Sep 1;66(5):807-12.
9
American Academy of Clinical Toxicology Practice Guidelines on the Treatment of Ethylene Glycol Poisoning. Ad Hoc Committee.美国临床毒理学学会乙二醇中毒治疗实践指南。特设委员会。
J Toxicol Clin Toxicol. 1999;37(5):537-60. doi: 10.1081/clt-100102445.
10
Fomepizole for the treatment of ethylene glycol poisoning. Methylpyrazole for Toxic Alcohols Study Group.用于治疗乙二醇中毒的甲吡唑。中毒性醇类研究组。
N Engl J Med. 1999 Mar 18;340(11):832-8. doi: 10.1056/NEJM199903183401102.

口服乙醇治疗乙二醇中毒

Treatment of Ethylene Glycol Poisoning with Oral Ethyl Alcohol.

作者信息

Achappa B, Madi D, Kanchan T, Kishanlal N K

机构信息

Associate Professor, Department of Internal Medicine, Kasturba Medical College, Manipal Academy of Higher Education, Mangalore, India.

Associate Professor, Department of Forensic Medicine & Toxicology, All India Institute of Medical Sciences, Jodhpur, India.

出版信息

Case Rep Med. 2019 Jan 30;2019:7985917. doi: 10.1155/2019/7985917. eCollection 2019.

DOI:10.1155/2019/7985917
PMID:30838047
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6374870/
Abstract

Ethylene glycol poisoning is not uncommon in India. The ill effects are primarily caused by its toxic metabolites: glycolic acid and oxalic acid. A 70-year-old female presented to our hospital with ataxia after ingestion of ethylene glycol. The reported case describes the management of ethylene glycol poisoning using oral ethyl alcohol as an alternative to the recommended intravenous ethyl alcohol and fomepizole that are not available for use in India. The need for high degree of clinical suspicion, targeted investigations, and early instigation of treatment is of prime importance in cases of ethylene glycol poisoning as it can lead to long-term complications or even death.

摘要

乙二醇中毒在印度并不罕见。其不良影响主要由其有毒代谢产物:乙醇酸和草酸引起。一名70岁女性在摄入乙二醇后因共济失调前来我院就诊。该报告病例描述了使用口服乙醇治疗乙二醇中毒的方法,以此替代在印度无法使用的推荐静脉注射乙醇和甲吡唑。对于乙二醇中毒病例,高度的临床怀疑、针对性检查以及早期启动治疗至关重要,因为它可能导致长期并发症甚至死亡。