Graduate Institute of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan, ROC.
Chander Clinic, Taipei, Taiwan, ROC.
J Chin Med Assoc. 2019 Jan;82(1):78-85. doi: 10.1016/j.jcma.2018.07.002.
Pulse diagnosis researches acquiring pulse waves from the wrist radial artery has not yet addressed the issue of whether this information is affected by differences in the hemodynamic characteristics of pressure waves derived from different locations. This study aimed to clarify whether the blood dynamic states are identical with regard to the "three positions and nine indicators" ((Equation is included in full-text article.)) listed in traditional Chinese medicine (TCM).
A total of 37 participants of CAD group and 20 participants of healthy group were recruited, and pressure pulse waves were measured at 18 locations on both hands. A multivariate analysis (MANOVA) was performed with a "randomized block design" using SPSS 22.0 and R 3.4.1 to examine the time-domain parameters that represented certain hemodynamic characteristics.
In CAD group, the results showed significant differences (p < 0.05) among the h1, h2, h3, h1/t, and h3/h1 measurements of the pulse waves using different indicators at the same position; the h1, h2, h3, and h1/t measurements of the pulse waves at different positions using the indicator "Superficial"; and the h1, h2, h3, h1/t, and h3/h1 measurements of the pulse waves at different positions using the indicator "Medium". In healthy group, the results showed significant differences (p < 0.05) among the h1, h2, h3, and h1/t measurements of the pulse waves using different indicators at the same position; the h1, h2, and h1/t measurements of the pulse waves at different positions using the same indicator.
Because of the differences in the hemodynamic characteristics among the different positions and indicators, the article might provide a new opinion for future pulse diagnosis investigations to carefully consider the measurement location to ensure the completeness of the information.
从腕部桡动脉获取脉象的脉搏诊断研究尚未解决源自不同位置的压力波的血流动力学特征差异是否会影响信息的问题。本研究旨在阐明中医（TCM）中列出的“三部九候”（（方程包含在全文中。））的 18 个手部位置的血流动力学状态是否相同。
共纳入 37 例 CAD 组和 20 例健康组参与者，测量双手 18 个部位的压力脉搏波。使用 SPSS 22.0 和 R 3.4.1 中的“随机区组设计”进行多元分析（MANOVA），检查代表特定血流动力学特征的时域参数。
在 CAD 组中，使用同一位置不同指标的脉搏波 h1、h2、h3、h1/t 和 h3/h1 测量值之间存在显著差异（p<0.05）；使用指标“浅层”的不同位置的脉搏波 h1、h2、h3 和 h1/t 测量值之间存在显著差异；以及使用指标“中层”的不同位置的脉搏波 h1、h2、h3、h1/t 和 h3/h1 测量值之间存在显著差异。在健康组中，使用同一位置不同指标的脉搏波 h1、h2、h3 和 h1/t 测量值之间存在显著差异；使用同一指标的不同位置的脉搏波 h1、h2 和 h1/t 测量值之间存在显著差异。
由于不同位置和指标的血流动力学特征存在差异，本文可能为未来的脉搏诊断研究提供新的观点，即仔细考虑测量位置以确保信息的完整性。
