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卡尔 - 彼得·哈德勒的流行病学模型

The epidemiological models of Karl-Peter Hadeler.

作者信息

Dietz Klaus

机构信息

Department of Medical Biometry (Emeritus), University of Tübingen, 72076, Tübingen, Germany.

出版信息

Infect Dis Model. 2018 Sep 26;3:171-175. doi: 10.1016/j.idm.2018.09.006. eCollection 2018.

DOI:10.1016/j.idm.2018.09.006
PMID:30839938
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6326227/
Abstract

The most frequently cited articles out of KP Hadeler's 45 papers with epidemiological applications are summarized. Parasitic diseases which increase the death rate of the hosts proportional to the integer number of parasites present were described by integral equations for the generating function of the age- and time-dependent number of parasites. A model was derived for a population structured by the continuous level of parasitic infection. Stimulated by the spread of AIDS a new class of epidemic models was developed which take into account explicitly the formation and separation of pairs. For predator-prey populations with parasitic infections threshold conditions for the persistence of the predator were derived. The interaction of epidemics and demography was analysed. Several epidemiological conditions led to backward bifurcations associated with multiple infective stationary states.

摘要

总结了KP·哈德勒45篇具有流行病学应用的论文中被引用频率最高的文章。通过关于年龄和时间相关寄生虫数量生成函数的积分方程,描述了与宿主体内寄生虫整数数量成正比增加宿主死亡率的寄生虫病。推导了一个由寄生虫感染连续水平构成的种群模型。受艾滋病传播的启发,开发了一类新的流行病模型,该模型明确考虑了配对的形成和分离。对于有寄生虫感染的捕食者 - 猎物种群,推导了捕食者持续存在的阈值条件。分析了流行病与人口统计学的相互作用。几种流行病学情况导致了与多个感染稳态相关的反向分岔。

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The epidemiological models of Karl-Peter Hadeler.卡尔 - 彼得·哈德勒的流行病学模型
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本文引用的文献

1
Pair formation models for sexually transmitted infections: A primer.性传播感染的配对形成模型:入门指南。
Infect Dis Model. 2017 Jul 25;2(3):368-378. doi: 10.1016/j.idm.2017.07.002. eCollection 2017 Aug.
2
Mathematical epidemiology: Past, present, and future.数学流行病学:过去、现在与未来。
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From homogeneous eigenvalue problems to two-sex population dynamics.从齐次特征值问题到两性种群动态
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Case fatality models for epidemics in growing populations.增长型人群中流行病的病死率模型。
Math Biosci. 2016 Nov;281:120-127. doi: 10.1016/j.mbs.2016.09.007. Epub 2016 Sep 23.
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Infectious disease agents mediate interaction in food webs and ecosystems.传染病原体在食物网和生态系统中介导相互作用。
Proc Biol Sci. 2014 Jan 8;281(1777):20132709. doi: 10.1098/rspb.2013.2709. Print 2014 Feb 22.
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Characterizing the next-generation matrix and basic reproduction number in ecological epidemiology.刻画生态流行病学中的下一代矩阵与基本再生数
J Math Biol. 2013 Mar;66(4-5):1045-64. doi: 10.1007/s00285-012-0602-1. Epub 2012 Oct 20.
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Quiescence, excitability, and heterogeneity in ecological models.
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Comparability of results from pair and classical model formulations for different sexually transmitted infections.不同性传播感染的配对模型和经典模型公式结果的可比性。
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On the eradicability of infections with partially protective vaccination in models with backward bifurcation.在具有后向分岔的模型中部分保护性疫苗接种对感染的根除作用
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