Chen Jia-Min, Yan Ying
Department of Prosthodontics, Guanghua School of Stomatology, Hospital of Stomatology, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Stomatology, Guangzhou 510055, Guangdong Province, China.
World J Clin Cases. 2019 Feb 26;7(4):516-524. doi: 10.12998/wjcc.v7.i4.516.
Bruxism is a jaw-muscle activity characterized by the clenching or grinding of teeth. It can be divided into nocturnal bruxism and diurnal bruxism (DB). DB secondary to antidepressants is rare and refractory. Reports associated with antidepressant-induced DB are mostly anecdotal without long-term follow-up. The effect of drug intervention on antidepressant-induced DB is still contested. We herein report the first case of successful treatment of venlafaxine-induced DB with an occlusal splint.
This case report describes detailed 7-year follow-up of a patient with venlafaxine-induced DB treated with an occlusal splint. The patient who complained about involuntary daytime tooth grinding after taking venlafaxine for a period of 4 mo and was diagnosed with venlafaxine-induced DB. Subsequently, an occlusal splint with modified bilateral buccal-pterygoid pads was used to treat his tooth grinding and to protect the dental structures from tooth wearing. The patient reported remission of symptoms after several months of treatment. His grinding activity was gradually and stably controlled after 2 years, with an almost complete recovery from DB after 6 years.
The maxillary buccal-pterygoid splint can be used as a noninvasive approach to treat venlafaxine-induced DB.
磨牙症是一种以牙齿紧咬或磨牙为特征的颌面部肌肉活动。它可分为夜间磨牙症和日间磨牙症（DB）。抗抑郁药所致的DB较为罕见且难以治疗。与抗抑郁药诱发DB相关的报道大多是轶事性的，缺乏长期随访。药物干预对抗抑郁药诱发DB的效果仍存在争议。我们在此报告首例使用咬合板成功治疗文拉法辛诱发DB的病例。
本病例报告详细描述了一名使用咬合板治疗的文拉法辛诱发DB患者的7年随访情况。该患者在服用文拉法辛4个月后出现白天不自主磨牙，被诊断为文拉法辛诱发的DB。随后，使用改良双侧颊翼突垫的咬合板治疗其磨牙症状，并保护牙齿结构免受磨损。患者在治疗数月后症状缓解。经过2年，其磨牙活动逐渐且稳定得到控制，6年后几乎完全从DB中恢复。
上颌颊翼突垫咬合板可作为一种非侵入性方法用于治疗文拉法辛诱发的DB。
