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[全氟碳化物乳剂输注过程中低氧血症时血气传质的变化]

[Changes in the mass transfer of blood gases in hypoxia during infusion of and emulsion of perfluorocarbons].

作者信息

Kuznetsova I N, Gerbut K A, Liagushkina L V

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1986 Feb;72(2):231-8.

PMID:3084306
Abstract

Systemic hemodynamic parameters, physico-chemical homeostasis and blood rheology were studied using the model of anemic hypoxia after substitution of the blood with salt solution exceeding the blood loss, with or without additional administration of perfluorocarbon (PFC) emulsion. The data obtained suggest that physiological reactions of O2 deficiency compensation in anemic hypoxia (increased O2 extraction, improved heart performance) can be substantially improved if the PFC emulsion is present in the blood flow as the PFC seems to enhance the mass transfer of blood gases.

摘要

使用超过失血量的盐溶液替代血液后造成贫血性缺氧模型,研究了全身血流动力学参数、理化稳态和血液流变学,同时给予或不给予全氟碳(PFC)乳剂。获得的数据表明,如果PFC乳剂存在于血流中,贫血性缺氧时氧气缺乏补偿的生理反应(增加氧气提取、改善心脏功能)可以得到显著改善,因为PFC似乎增强了血气的传质。

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