Division of Infectious Disease (Transplant/Oncology), Johns Hopkins, Baltimore, Maryland.
Division of Pediatric Infectious Diseases, UPMC Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania.
Clin Transplant. 2019 Sep;33(9):e13519. doi: 10.1111/ctr.13519. Epub 2019 Apr 6.
The present AST-IDCOP guidelines update information on strategies for safe living after organ transplantation. While transplantation carries an increased risk for infection from the recipient's environment due to lifelong immunosuppression, the goal is for the recipient to be able to return to their home and live as normal a life as possible with a functioning graft. The current guideline provides updates to prior recommendations including additions on infections from water and food sources, exposures to animals, cannabis use as well as sexual exposures or those encountered with travel. Similar to the prior editions, many of the recommendations are based on good infection prevention standards, extrapolation from other immunocompromised hosts, and risks found from cases series in transplant patients. Enhanced education and attention to incorporating safe living strategies into daily life should help to accomplish successful transplant with recipients achieving a fulfilling life away from the hospital.
目前的 AST-IDCOP 指南更新了器官移植后安全生活策略的信息。虽然由于终身免疫抑制,移植会使受者从环境中感染的风险增加,但目标是让受者能够回到家中,并在功能正常的移植物的情况下尽可能正常地生活。本指南更新了先前的建议,包括增加了来自水和食物来源的感染、与动物接触、大麻使用以及性接触或旅行中遇到的感染。与之前的版本一样,许多建议都是基于良好的感染预防标准、从其他免疫功能低下的宿主推断以及从移植患者的病例系列中发现的风险。增强教育并关注将安全生活策略融入日常生活中,应该有助于实现成功的移植,使受者远离医院过上充实的生活。