Suppr超能文献

养老院中 HIV 感染者的身体功能轨迹。

Trajectory of Physical Functioning Among Persons Living With HIV in Nursing Homes.

机构信息

Department of Public Health Sciences, University of Rochester Medical Center, Rochester, NY.

Health Services, Policy & Practice, Center for Gerontology & Healthcare Research, Brown University School of Public Health, Providence, RI.

出版信息

J Am Med Dir Assoc. 2019 Apr;20(4):497-502. doi: 10.1016/j.jamda.2019.01.126. Epub 2019 Mar 4.

Abstract

OBJECTIVE(S): To examine the change in physical functional status among persons living with HIV (PLWH) in nursing homes (NHs) and how change varies with age and dementia.

DESIGN

Retrospective cohort study.

SETTING

NHs in 14 states in the United States.

PARTICIPANTS

PLWH who were admitted to NHs between 2001 and 2010 and had stays of ≥90 days (N = 3550).

MEASUREMENTS

We linked Medicaid Analytic eXtract (MAX) and Minimum Data Set (MDS) data for NH residents in the sampled states and years and used them to determine HIV infection. The main outcome was improvement in physical functional status, defined as a decrease of at least 4 points in the activities of daily living (ADL) score within 90 days of NH admission. Independent variables of interest were age and dementia (Alzheimer's disease or other dementia). Multivariate logistic regression was used, adjusting for individual-level covariates.

RESULTS

The average age on NH admission of PLWH was 58. Dementia prevalence ranged from 14.5% in the youngest age group (age <40 years) to 38.9% in the oldest group (age ≥70 years). Overall, 44% of the PLWH experienced ADL improvement in NHs. Controlling for covariates, dementia was related to a significantly lower likelihood of ADL improvement among PLWH in the oldest age group only: the adjusted probability of improvement was 40.6% among those without dementia and 29.3% among those with dementia (P < .01).

CONCLUSIONS/RELEVANCE: PLWH, especially younger persons, may be able to improve their ADL function after being admitted into NHs. However, with older age, PLWH with dementia are more physically dependent and vulnerable to deterioration of physical functioning in NHs. More and/or specialized care may be needed to maintain physical functioning among this population. Findings from this study provide NHs with information on care needs of PLWH and inform future research on developing interventions to improve care for PLWH in NHs.

摘要

目的

研究养老院(NH)中 HIV 感染者(PLWH)的身体功能状态变化,以及这种变化如何随年龄和痴呆症而变化。

设计

回顾性队列研究。

地点

美国 14 个州的 NH。

参与者

2001 年至 2010 年间入住 NH 且住院时间≥90 天的 PLWH(N=3550)。

测量

我们将样本州和年份的 Medicaid Analytic eXtract(MAX)和最小数据集中 NH 居民的数据进行链接,并使用这些数据来确定 HIV 感染情况。主要结果是身体功能状态的改善,定义为 NH 入院后 90 天内日常生活活动(ADL)评分至少下降 4 分。感兴趣的自变量为年龄和痴呆症(阿尔茨海默病或其他痴呆症)。采用多变量逻辑回归,调整个体水平的协变量。

结果

PLWH 入住 NH 时的平均年龄为 58 岁。痴呆症的患病率在年龄最小的组(<40 岁)为 14.5%,在年龄最大的组(≥70 岁)为 38.9%。总体而言,44%的 PLWH 在 NH 中 ADL 得到改善。在控制协变量的情况下,痴呆症与 PLWH 中年龄最大组 ADL 改善的可能性显著降低有关:无痴呆症者的调整后改善概率为 40.6%,痴呆症者为 29.3%(P<.01)。

结论/相关性:PLWH,尤其是较年轻者,在入住 NH 后可能能够改善其 ADL 功能。然而,随着年龄的增长,患有痴呆症的 PLWH 身体依赖性更强,更容易在 NH 中身体功能恶化。可能需要更多和/或专门的护理来维持这一人群的身体功能。这项研究的结果为 NH 提供了有关 PLWH 护理需求的信息,并为未来研究开发改善 NH 中 PLWH 护理的干预措施提供了信息。

相似文献

1
Trajectory of Physical Functioning Among Persons Living With HIV in Nursing Homes.
J Am Med Dir Assoc. 2019 Apr;20(4):497-502. doi: 10.1016/j.jamda.2019.01.126. Epub 2019 Mar 4.
2
Nursing Home Residents by Human Immunodeficiency Virus Status: Characteristics, Dementia Diagnoses, and Antipsychotic Use.
J Am Geriatr Soc. 2019 Jul;67(7):1353-1360. doi: 10.1111/jgs.15949. Epub 2019 May 7.
3
People Living With HIV in U.S. Nursing Homes in the Fourth Decade of the Epidemic.
J Assoc Nurses AIDS Care. 2019 Jan-Feb;30(1):20-34. doi: 10.1097/JNC.0000000000000033.
4
End-of-Life Care among Nursing Home Residents with Dementia Varies by Nursing Home and Market Characteristics.
J Am Med Dir Assoc. 2021 Feb;22(2):320-328.e4. doi: 10.1016/j.jamda.2020.06.021. Epub 2020 Jul 28.
6
Exercise or Social Intervention for Nursing Home Residents with Dementia: A Pilot Randomized, Controlled Trial.
J Am Geriatr Soc. 2017 Sep;65(9):E123-E129. doi: 10.1111/jgs.14947. Epub 2017 May 19.
8
Effects of cognitive performance on change in physical function in long-stay nursing home residents.
J Gerontol A Biol Sci Med Sci. 2002 Dec;57(12):M778-84. doi: 10.1093/gerona/57.12.m778.
9
Telemedicine Utilization Among Residents With Alzheimer Disease and Related Dementia: Association With Nursing Home Characteristics.
J Am Med Dir Assoc. 2024 Sep;25(9):105152. doi: 10.1016/j.jamda.2024.105152. Epub 2024 Jul 14.
10
Validity and responsiveness of the Minimum Data Set.
J Am Geriatr Soc. 1999 Aug;47(8):1000-4. doi: 10.1111/j.1532-5415.1999.tb01297.x.

引用本文的文献

1
Treatment Regimens and Care Models for Older Patients Living with HIV: Are We Doing Enough?
HIV AIDS (Auckl). 2023 Apr 29;15:191-208. doi: 10.2147/HIV.S311613. eCollection 2023.
2
The Quality of Nursing Homes That Serve Patients With Human Immunodeficiency Virus.
J Am Geriatr Soc. 2019 Dec;67(12):2615-2621. doi: 10.1111/jgs.16155. Epub 2019 Aug 29.

本文引用的文献

1
Ten-year trends in antiretroviral therapy persistence among US Medicaid beneficiaries.
AIDS. 2017 Jul 31;31(12):1697-1707. doi: 10.1097/QAD.0000000000001541.
2
A growing need - HIV education in long-term care.
Geriatr Nurs. 2017 May-Jun;38(3):199-206. doi: 10.1016/j.gerinurse.2016.10.014. Epub 2017 Feb 4.
3
Assessment of Activities of Daily Living, Self-Care, and Independence.
Arch Clin Neuropsychol. 2016 Sep;31(6):506-16. doi: 10.1093/arclin/acw049. Epub 2016 Jul 29.
4
Long-Term Care Services in the United States: 2013 Overview.
Vital Health Stat 3. 2013 Dec(37):1-107.
6
Cohort Profile: Recruitment cohorts in the neuropsychological substudy of the Multicenter AIDS Cohort Study.
Int J Epidemiol. 2015 Oct;44(5):1506-16. doi: 10.1093/ije/dyu092. Epub 2014 Apr 24.
7
Age, comorbidities, and AIDS predict a frailty phenotype in men who have sex with men.
J Gerontol A Biol Sci Med Sci. 2014 Feb;69(2):189-98. doi: 10.1093/gerona/glt148. Epub 2013 Oct 14.
8
Growing older with HIV/AIDS: new public health challenges.
Am J Public Health. 2013 Mar;103(3):e7-e15. doi: 10.2105/AJPH.2012.301161. Epub 2013 Jan 17.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验