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A clinico-molecular predictor identifies follicular lymphoma patients at risk of early transformation after first-line immunotherapy.

作者信息

Steen Chloé B, Leich Ellen, Myklebust June H, Lockmer Sandra, Wise Jillian F, Wahlin Björn E, Østenstad Bjørn, Liestøl Knut, Kimby Eva, Rosenwald Andreas, Smeland Erlend B, Holte Harald, Lingjærde Ole Christian, Brodtkorb Marianne

机构信息

Department of Informatics, University of Oslo, Oslo, Norway.

Department of Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.

出版信息

Haematologica. 2019 Oct;104(10):e460-e464. doi: 10.3324/haematol.2018.209080. Epub 2019 Mar 7.

DOI:10.3324/haematol.2018.209080
PMID:30846496
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6886427/
Abstract
摘要

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本文引用的文献

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Chemotherapy-Free Initial Treatment of Advanced Indolent Lymphoma Has Durable Effect With Low Toxicity: Results From Two Nordic Lymphoma Group Trials With More Than 10 Years of Follow-Up.晚期惰性淋巴瘤的无化疗初始治疗具有持久疗效且毒性低：两项北欧淋巴瘤小组试验超过10年随访结果
J Clin Oncol. 2018 Oct 4:JCO1800262. doi: 10.1200/JCO.18.00262.
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Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling.通过单细胞分析确定非霍奇金淋巴瘤中B细胞受体信号传导的不同模式。
Blood. 2017 Feb 9;129(6):759-770. doi: 10.1182/blood-2016-05-718494. Epub 2016 Dec 23.
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Pathogenic role of B-cell receptor signaling and canonical NF-κB activation in mantle cell lymphoma.B细胞受体信号传导和经典核因子κB激活在套细胞淋巴瘤中的致病作用
Blood. 2016 Jul 7;128(1):82-92. doi: 10.1182/blood-2015-11-681460. Epub 2016 Apr 28.
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Integration of gene mutations in risk prognostication for patients receiving first-line immunochemotherapy for follicular lymphoma: a retrospective analysis of a prospective clinical trial and validation in a population-based registry.在接受一线免疫化疗的滤泡性淋巴瘤患者中，基因突变更新预后风险预测：一项前瞻性临床试验的回顾性分析及基于人群的登记处验证。
Lancet Oncol. 2015 Sep;16(9):1111-1122. doi: 10.1016/S1470-2045(15)00169-2. Epub 2015 Aug 6.
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Two courses of four weekly infusions of rituximab with or without interferon-α2a: final results from a randomized phase III study in symptomatic indolent B-cell lymphomas.利妥昔单抗联合或不联合干扰素-α2a进行的两个疗程、每周一次共四周的输注：一项针对有症状的惰性B细胞淋巴瘤的随机III期研究的最终结果
Leuk Lymphoma. 2015;56(9):2598-607. doi: 10.3109/10428194.2015.1014363. Epub 2015 Mar 11.
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Transformed follicular non-Hodgkin lymphoma.转化滤泡性非霍奇金淋巴瘤。
Blood. 2015 Jan 1;125(1):40-7. doi: 10.1182/blood-2014-04-516815. Epub 2014 Dec 11.
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Blood. 2014 Feb 13;123(7):1051-4. doi: 10.1182/blood-2013-07-512392. Epub 2013 Dec 19.
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Rates and outcomes of follicular lymphoma transformation in the immunochemotherapy era: a report from the University of Iowa/MayoClinic Specialized Program of Research Excellence Molecular Epidemiology Resource.免疫化疗时代滤泡性淋巴瘤转化的发生率和结局：来自爱荷华大学/梅奥诊所卓越研究计划分子流行病学资源的报告。
J Clin Oncol. 2013 Sep 10;31(26):3272-8. doi: 10.1200/JCO.2012.48.3990. Epub 2013 Jul 29.
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Improvements in observed and relative survival in follicular grade 1-2 lymphoma during 4 decades: the Stanford University experience.4 个十年期间滤泡性 1-2 级淋巴瘤观察到和相对生存率的改善：斯坦福大学的经验。
Blood. 2013 Aug 8;122(6):981-7. doi: 10.1182/blood-2013-03-491514. Epub 2013 Jun 18.
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Chronic active B-cell-receptor signalling in diffuse large B-cell lymphoma.弥漫性大 B 细胞淋巴瘤中慢性活性 B 细胞受体信号转导。
Nature. 2010 Jan 7;463(7277):88-92. doi: 10.1038/nature08638.