胶质母细胞瘤的颅外转移——两个病例故事

Schou Nørøxe Dorte, Regner Michaelsen Signe, Broholm Helle, Møller Søren, Skovgaard Poulsen Hans, Lassen Ulrik

Department of Radiation Biology Rigshospitalet Copenhagen Denmark.

Department of Oncology Rigshospitalet Copenhagen Denmark.

Clin Case Rep. 2018 Dec 27;7(2):289-294. doi: 10.1002/ccr3.1980. eCollection 2019 Feb.

The clinician should always consider extracranial metastases in glioblastoma. Increased risk factors are young age at diagnosis, histology of gliosarcoma, and prior intracranial tumor surgery. Clinical guidelines are needed for this rare event, including consideration for prophylactic intervention.

临床医生在治疗胶质母细胞瘤时应始终考虑颅外转移的情况。增加的风险因素包括诊断时年龄较轻、胶质肉瘤的组织学类型以及既往有颅内肿瘤手术史。对于这种罕见情况需要临床指南，包括考虑进行预防性干预。