寨卡病毒感染：基础与临床方面综述文章
Zika Virus Infection, Basic and Clinical Aspects: A Review Article.
作者信息
Noorbakhsh Farshid, Abdolmohammadi Kamal, Fatahi Yousef, Dalili Hossein, Rasoolinejad Mehrnaz, Rezaei Farshid, Salehi-Vaziri Mostafa, Shafiei-Jandaghi Nazanin Zahra, Gooshki Ehsan Shamsi, Zaim Morteza, Nicknam Mohammad Hossein
机构信息
Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Department of Immunology, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran.
出版信息
Iran J Public Health. 2019 Jan;48(1):20-31.
BACKGROUND
Zika virus infection has recently attracted the attention of medical community. While clinical manifestations of the infection in adult cases are not severe and disease is not associated with high mortality rates, Zika virus infection can have an impact on fetal development and lead to severe neurodevelopmental abnormalities.
METHODS
To gain insight into different aspects of Zika virus infection, a comprehensive literature review was performed. With regard to epidemiology and geographical distribution of Zika virus infection, relevant information was extracted from CDC and WHO websites.
RESULTS
In this review, we discuss different basic and clinical aspects of Zika virus infection including virology, epidemiology and pathogenesis of disease. Laboratory methods required for the diagnosis of disease together with ethical issues associated with Zika virus infection will also be discussed in detail.
CONCLUSION
Herein, we have tried to provide a multi-faceted view of Zika virus infection, with greater emphasis on disease status in Eastern Mediterranean Region.
背景
寨卡病毒感染最近引起了医学界的关注。虽然成人感染该病毒的临床表现并不严重，且疾病与高死亡率无关，但寨卡病毒感染会对胎儿发育产生影响，并导致严重的神经发育异常。
方法
为深入了解寨卡病毒感染的不同方面，进行了全面的文献综述。关于寨卡病毒感染的流行病学和地理分布，从美国疾病控制与预防中心（CDC）和世界卫生组织（WHO）网站提取了相关信息。
结果
在本综述中，我们讨论了寨卡病毒感染的不同基础和临床方面，包括病毒学、疾病的流行病学和发病机制。还将详细讨论疾病诊断所需的实验室方法以及与寨卡病毒感染相关的伦理问题。
结论
在此，我们试图提供寨卡病毒感染的多方面观点，更侧重于东地中海地区的疾病状况。
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