Department of Psychology, University of Georgia, Athens, GA, USA.
Department of Medical and Clinical Psychology, Uniformed Services University, Bethesda, MD, USA.
Soc Cogn Affect Neurosci. 2019 May 17;14(4):381-395. doi: 10.1093/scan/nsz017.
This study is a replication of an existing large study (N = 507) on the surface-based morphometric correlates of five-factor model (FFM) personality traits. The same methods were used as the original study in another large sample drawn from the same population (N = 597) with results then being aggregated from both samples (N = 1104), providing the largest investigation into the neuroanatomical correlates of FFM personality traits to date. Clusters of association between brain morphometry and each FFM trait are reported. For neuroticism, agreeableness, openness and conscientiousness clusters of association were found in the dorsolateral prefrontal cortex for at least one morphometric index. Morphometry in various other regions was also associated with each personality trait. While some regions found in the original study were confirmed in the replication and full samples, others were not, highlighting the importance of replicating even high-quality, well-powered studies. Effect sizes were very similar in the replication and whole samples as those found in the original study. As a whole, the current results provide the strongest evidence to date on the neuroanatomical correlates of personality and highlights challenges in using this approach to understanding the neural correlates of personality.
这项研究复制了一项现有的大型研究（N=507），研究的是五因素模型（FFM）人格特质的基于表面的形态计量学相关性。与原始研究一样，在来自同一人群的另一个大样本中（N=597）使用相同的方法，然后将两个样本的结果汇总（N=1104），这是迄今为止对 FFM 人格特质的神经解剖学相关性进行的最大规模调查。报告了大脑形态计量学与每个 FFM 特质之间的关联簇。对于神经质、宜人性、开放性和尽责性，在至少一个形态计量指数上，发现了与背外侧前额叶皮层相关的关联簇。其他各种区域的形态计量学也与每个人格特质相关。虽然在原始研究中发现的一些区域在复制和全样本中得到了证实，但其他区域没有，这突出了即使是高质量、高功率的研究也需要复制的重要性。复制和全样本中的效应大小与原始研究中发现的非常相似。总的来说，目前的结果提供了迄今为止人格神经解剖学相关性的最强证据，并强调了使用这种方法理解人格的神经相关性所面临的挑战。
