Levy W J, Latchaw J, Hahn J F, Sawhny B, Bay J, Dohn D F
Neurosurgery. 1986 Mar;18(3):331-4. doi: 10.1227/00006123-198603000-00013.
A series of 66 spinal cord neurofibromas was analyzed for history, signs, surgical approach, and outcome. The tumors presented primarily with sensory symptoms. Plain films were abnormal in 1/2 of cases and 1/2 had a complete block. They were primarily intradural, and primarily thoracic. A conservative exam system was used for follow-up and 85% with pain had complete relief; 50% with motor loss had normal motor function, and 88% had normal sensation who had prior sensory loss. In comparison to meningiomas, the principal differences were that neurofibromas had an even sex distribution, a lower incidence of cord signs and symptoms, more frequent findings on plain x-rays, and higher cerebrospinal fluid protein. Surgical outcome was similar. Sacrifice of the involved root during removal usually did not produce a deficit. The series is compared with a similar series of meningiomas from the same institution over the same time period.
对66例脊髓神经纤维瘤患者的病史、体征、手术方式及预后进行了分析。这些肿瘤主要表现为感觉症状。半数病例的X线平片异常，半数出现完全性梗阻。肿瘤主要位于硬膜内，且主要位于胸段。采用保守的检查系统进行随访，85%有疼痛的患者疼痛完全缓解；50%有运动功能丧失的患者运动功能恢复正常，88%先前有感觉丧失的患者感觉恢复正常。与脑膜瘤相比，主要差异在于神经纤维瘤的性别分布均匀，脊髓体征和症状的发生率较低，X线平片上的发现更常见，脑脊液蛋白含量更高。手术预后相似。切除肿瘤时牺牲受累神经根通常不会导致功能缺损。将该系列病例与同一机构在同一时期的一系列类似脑膜瘤病例进行了比较。
