Department of Neuroscience, Uppsala University, Sleep Research Laboratory, Uppsala, Sweden.
Department of Medical Sciences, Respiratory, Allergy and Sleep Research, Uppsala University, Uppsala, Sweden.
J Clin Sleep Med. 2019 Mar 15;15(3):431-435. doi: 10.5664/jcsm.7668.
The current study sought to examine whether self-reported sleep duration is linked to an adverse body composition in 19,709 adults aged 45 to 75 years.
All variables used in the current study were derived from the Swedish EpiHealth cohort study. Habitual sleep duration was measured by questionnaires. Body composition was assessed by bioimpedance. The main outcome variables were fat mass and fat-free mass (in kg). Analysis of covariance adjusting for age, sex, fat mass in the case of fat-free mass (and vice versa), leisure time physical activity, smoking, and alcohol consumption was used to investigate the association between sleep duration and body composition.
Short sleep (defined as ≤ 5 hours sleep per day) and long sleep (defined as 8 or more hours of sleep per day) were associated with lower fat-free mass and higher fat mass, compared with 6 to 7 hours of sleep duration ( < .05).
These observations could suggest that both habitual short and long sleep may contribute to two common clinical phenotypes in middle-aged and older humans, ie, body adiposity and sarcopenia. However, the observational nature of our study does not allow for causal interpretation.
本研究旨在探讨 19709 名 45 至 75 岁成年人中，自我报告的睡眠时间与不良身体成分之间的关系。
本研究中使用的所有变量均源自瑞典 EpiHealth 队列研究。习惯性睡眠时间通过问卷调查进行测量。身体成分通过生物阻抗法进行评估。主要观察指标为脂肪量和去脂体重（kg）。采用协方差分析调整年龄、性别、去脂体重中的脂肪量（反之亦然）、休闲时间体力活动、吸烟和饮酒，以探讨睡眠时间与身体成分之间的关系。
与每天 6 至 7 小时的睡眠时间相比，短睡眠（定义为每天睡眠≤5 小时）和长睡眠（定义为每天睡眠 8 小时或更长时间）与较低的去脂体重和较高的脂肪量相关（<0.05）。
这些观察结果表明，习惯性短睡和长睡可能导致中年和老年人两种常见的临床表型，即身体肥胖和肌肉减少症。然而，我们研究的观察性质不允许进行因果解释。
