Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea.
Department of Medicine, Graduate School, Yonsei University, Seoul, Republic of Korea.
J Clin Sleep Med. 2017 Sep 15;13(9):1097-1104. doi: 10.5664/jcsm.6732.
Sarcopenia, or loss of muscle mass, occurs with aging and results in frailty, disability, cardiovascular disease, and insulin resistance. Recently, researchers have asserted that sarcopenia is not an inevitable process, but is a modifiable condition. Adequate sleep duration is also important to maintain good physical and mental health. Therefore, the aim of our study was to examine the association between sleep duration and sarcopenia in Korean adults.
Data from 16,148 participants (7,158 men and 8,990 women) were analyzed from the 2008-2011 Korean National Health and Nutrition Examination Survey (KNHANES). We defined sarcopenia as one standard deviation below the sex-specific means of the appendicular skeletal muscle/height-squared values of a young reference group. Participants were categorized into 5 groups according to sleep duration. The odds ratios (OR) and 95% confidence intervals (95% CI) for sarcopenia according to sleep duration were calculated using multiple logistic regression analysis.
The prevalence of sarcopenia was 14.3% in the total population (males 18.7%, females 9.7%). Compared to the 7 hours of sleep group, the OR (95% CI) for sarcopenia of the long sleep duration group (9 hours or more) was 1.589 (1.100-2.295) after controlling for confounding factors. From the results of subgroup analysis, high-risk groups for sarcopenia are as follows: 40-64 years old (OR = 1.868), normal body mass index (OR = 1.516), smoking (OR = 2.219), no regular exercise (OR = 1.506) in long sleepers.
Long sleep duration (9 hours or longer) is independently associated with sarcopenia in Korean adults.
肌肉减少症，即肌肉量的减少，随着年龄的增长而发生，导致虚弱、残疾、心血管疾病和胰岛素抵抗。最近，研究人员断言，肌肉减少症不是一个不可避免的过程，而是一种可改变的状况。充足的睡眠时间对于保持良好的身心健康也很重要。因此，我们的研究旨在探讨韩国成年人的睡眠时间与肌肉减少症之间的关系。
我们对 2008-2011 年韩国国家健康和营养调查（KNHANES）的数据进行了分析，共纳入了 16148 名参与者（男性 7158 人，女性 8990 人）。我们将肌肉减少症定义为年轻参考组四肢骨骼肌/身高平方值的性别特定平均值减去一个标准差。根据睡眠时间将参与者分为 5 组。使用多因素 logistic 回归分析计算了睡眠时间与肌肉减少症之间的比值比（OR）和 95%置信区间（95%CI）。
总人群中肌肉减少症的患病率为 14.3%（男性 18.7%，女性 9.7%）。与睡眠时间为 7 小时的组相比，在控制了混杂因素后，睡眠时间长（9 小时或更长）组的肌肉减少症的 OR（95%CI）为 1.589（1.100-2.295）。从亚组分析的结果来看，肌肉减少症的高危人群如下：40-64 岁（OR=1.868）、正常体重指数（OR=1.516）、吸烟（OR=2.219）、无规律运动（OR=1.506）的长睡眠者。
韩国成年人的长睡眠时间（9 小时或更长）与肌肉减少症独立相关。
