Ramos Khara M, Rommelfanger Karen S, Greely Henry T, Koroshetz Walter J
National Institute of Neurological Disorders and Stroke, 31 Center Dr, MSC 2540, Bethesda, MD 20892, 301-594-2614,
Emory University School of Medicine, Departments of Neurology and Psychiatry and Behavioral Sciences, Emory Center for Ethics Neuroethics Program, Atlanta, GA 30322, (404) 727-1150,
J Responsible Innov. 2018;5(1):122-130. doi: 10.1080/23299460.2017.1319035. Epub 2017 May 5.
The Brain Research through Advancing Innovative Neurotechnologies® (BRAIN) Initiative is focused on developing new tools and neurotechnologies to revolutionize our understanding of how the brain functions in health and disease, in large part to address the growing societal impact of neurological, mental health, and substance abuse disorders. Recent advances in neurotechnology are delivering unprecedented ways to interrogate and modulate brain function, and the BRAIN Initiative is focused on translation for human medical uses over the next decade. Since its inception, the NIH component of the BRAIN Initiative has utilized an iterative model of integrating ethics into the scientific trajectory of the Initiative, most recently with the creation of a Neuroethics Division of the NIH BRAIN Initiative Multi-Council Working Group. The Division serves as a resource of expertise, to help the BRAIN Initiative navigate issues involving ethics. Here we discuss the BRAIN Initiative, and its implications and aspirations for neuroethics. We also discuss new opportunities for collaboration and for integrating stakeholder voices.
推进创新神经技术脑研究计划(BRAIN计划)专注于开发新工具和神经技术,以彻底改变我们对大脑在健康和疾病状态下如何运作的理解,这在很大程度上是为了应对神经、心理健康和药物滥用障碍对社会日益增长的影响。神经技术的最新进展正在提供前所未有的方式来探究和调节大脑功能,而BRAIN计划则专注于在未来十年将其转化为人类医学用途。自成立以来,BRAIN计划的美国国立卫生研究院(NIH)部分采用了一种将伦理融入该计划科学轨迹的迭代模式,最近成立了NIH BRAIN计划多理事会工作组神经伦理学部。该部门作为专业知识资源,帮助BRAIN计划应对涉及伦理的问题。在此,我们讨论BRAIN计划及其对神经伦理的影响和期望。我们还讨论了合作以及整合利益相关者声音的新机会。