Svartling N, Pfäffli P, Tarkkanen L
Arch Orthop Trauma Surg (1978). 1986;105(1):36-9. doi: 10.1007/BF00625658.
The blood levels and the half-life of monomeric methylmethacrylate after tourniquet release were studied in nine patients with osteoarthrosis or rheumatoid arthritis of the knee joint, treated with the Townley prosthesis under spinal anesthesia. Several ventricular extrasystoles were monitored in one patient with high blood levels of monomeric methylmethacrylate (119.80 micrograms/ml). The blood levels of monomeric methylmethacrylate ranged between 0.10 and 1.44 microgram/ml in the rest of the patients. The half-life of monomeric methylmethacrylate in vivo was 47-55 min.
在9例膝关节骨关节炎或类风湿性关节炎患者中，研究了在脊髓麻醉下使用汤利假体治疗后，止血带松开后单体甲基丙烯酸甲酯的血药浓度和半衰期。在1例单体甲基丙烯酸甲酯血药浓度较高（119.80微克/毫升）的患者中监测到几次室性早搏。其余患者单体甲基丙烯酸甲酯的血药浓度在0.10至1.44微克/毫升之间。单体甲基丙烯酸甲酯在体内的半衰期为47 - 55分钟。
