Goren T, Fischer D G, Rubinstein M
Biochim Biophys Acta. 1986 Jun 16;887(1):80-5. doi: 10.1016/0167-4889(86)90125-4.
The effect of pretreatment with interferon (IFN) ('priming') on the production of individual IFN subtypes was studied in subpopulations of human peripheral blood mononuclear cells and in the myeloid cell line KG-1. It was found that priming had a selective enhancing effect on the production of certain IFN-alpha subtypes (IFN-alpha 20K and IFN-alpha 21K) and not on others. KG-1 cells produce both IFN-alpha and -beta; however, only the production of IFN-alpha was enhanced by priming with either IFN-alpha, beta or gamma.
在人外周血单个核细胞亚群和髓系细胞系KG-1中研究了用干扰素（IFN）预处理（“启动”）对各IFN亚型产生的影响。发现启动对某些IFN-α亚型（IFN-α 20K和IFN-α 21K）的产生有选择性增强作用，而对其他亚型则无此作用。KG-1细胞可产生IFN-α和IFN-β；然而，用IFN-α、β或γ启动仅增强了IFN-α的产生。
