Enginar Ayşe Ünal, Karaman Nehir Samancı, Karakaş Ayşe Akman
Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Akdeniz University School of Medicine, Antalya, Turkey.
Department of Dermatology and Venereology, Akdeniz University School of Medicine, Antalya, Turkey.
Reumatologia. 2019;57(1):63-65. doi: 10.5114/reum.2019.83243. Epub 2019 Feb 28.
Laugier-Hunziker syndrome is a rare benign idiopathic condition characterized by acquired macular pigmentation of the lips and buccal mucosa, often accompanied by melanonychia. Although the etiopathogenesis is not fully known, tyrosine is thought to be responsible for the pathogenesis of enzyme hyperactivity in melanin biosynthesis. We present the case of a 66-year-old woman diagnosed with Laugier-Hunziker syndrome and rheumatoid arthritis.
劳吉尔-杭齐克尔综合征是一种罕见的良性特发性疾病,其特征为唇部和颊黏膜出现后天性黄斑色素沉着,常伴有甲床黑素沉着。尽管其发病机制尚未完全明确,但酪氨酸被认为是黑色素生物合成中酶活性过高的发病原因。我们报告一例66岁女性,诊断为劳吉尔-杭齐克尔综合征和类风湿关节炎。