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[干燥综合征患者并发劳吉耶-杭齐克尔综合征:1例报告]

[Laugier-Hunziker syndrome in a patient with Sjögren’s syndrome: Report of one case].

作者信息

Fajre Ximena, Aspillaga María, McNab María, Navarrete Jorge, Sanhueza Verónica, Benedetto Juana

出版信息

Rev Med Chil. 2016 May;144(5):671-4. doi: 10.4067/S0034-98872016000500017.

Abstract

Laugier-Hunziker syndrome is a rare benign idiopathic condition characterized by acquired macular pigmentation of lips and buccal mucosa, often accompanied with melanonychia. The main concern with this condition is to rule out other differential diagnosis with systemic repercussions and similar hyperpigmentation patterns, such as Peutz-Jeghers syndrome, adrenal insufficiency and melanoma. We report a 58-year-old female with a 20-year history of Sjögren’s syndrome, presenting with melanonychia and hyperpigmentation in the buccal mucosa. She had no relevant medication history and is a non-smoker. The patient denied any other symptoms. The histopathology confirmed the diagnosis of Laugier-Hunziker syndrome.

摘要

劳吉尔-杭齐克尔综合征是一种罕见的良性特发性疾病,其特征为唇部和颊黏膜出现后天性黄斑色素沉着,常伴有甲下黑素沉着。这种疾病的主要关注点是排除其他具有全身影响和类似色素沉着模式的鉴别诊断,如黑斑息肉综合征、肾上腺功能不全和黑色素瘤。我们报告一名58岁女性,有20年干燥综合征病史,出现甲下黑素沉着和颊黏膜色素沉着。她无相关用药史,不吸烟。患者否认有任何其他症状。组织病理学确诊为劳吉尔-杭齐克尔综合征。

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