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劳吉尔-杭齐克尔综合征——病例报告。

Laugier-Hunziker syndrome--Case report.

作者信息

Lalosevic Jovan, Zivanovic Dubravka, Skiljevic Dusan, Medenica Ljiljana

机构信息

Clinical Center of Serbia, Belgrade, RS.

出版信息

An Bras Dermatol. 2015 May-Jun;90(3 Suppl 1):223-5. doi: 10.1590/abd1806-4841.20153840.

Abstract

Laugier-Hunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. We present the case of a 63-year-old female with progressive, asymptomatic hyperpigmentation of buccal mucosa and a 7-year history of hyperpigmentation in several fingernails. Laugier-Hunziker syndrome was diagnosed based on the clinical features presented, dermoscopic findings and exclusion of underlying systemic diseases. Laugier-Hunziker syndrome is regarded as a diagnosis of exclusion. By identifying Laugier-Hunziker syndrome, other, more severe syndromes associated with hyperpigmentations can be excluded, namely Addison's disease and Peutz-Jeghers syndrome.

摘要

劳吉尔-杭齐克尔综合征是一种罕见的后天性疾病,其特征为口腔黏膜出现扁豆状色素沉着及甲纵嵴黑甲。我们报告一例63岁女性病例,其颊黏膜有进行性、无症状色素沉着,多个指甲有7年色素沉着病史。根据所呈现的临床特征、皮肤镜检查结果及排除潜在的全身性疾病,诊断为劳吉尔-杭齐克尔综合征。劳吉尔-杭齐克尔综合征被视为一种排除性诊断。通过确诊劳吉尔-杭齐克尔综合征,可以排除其他与色素沉着相关的更严重综合征,即艾迪生病和黑斑息肉综合征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9f3/4540557/32dfaf8fc76b/abd-90-03-s1-0223-g01.jpg

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