Department of Kinesiology, Faculty of Physiotherapy, University School of Physical Education, Al. I.J. Paderewskiego 35, Building P4, 51-612 Wroclaw, Poland.
Division of Biokinesiology and Physical Therapy and Department of Neurology, University of Southern California, Los Angeles, CA 90033, USA.
Int J Environ Res Public Health. 2019 Mar 11;16(5):880. doi: 10.3390/ijerph16050880.
This study examined the generalized effects of cycle ergometer aerobic interval training (AIT) on psychomotor behaviors in individuals with Parkinson's disease (PD), including bimanual motor control, cognitive function, and neurological motor and non-motor parkinsonian signs.
Twenty mild to moderate PD patients were randomly allocated to the following groups: (1) trained group (PD-TR, = 10), which besides receiving usual care, underwent an 8-week moderate intensity AIT program; or (2) control group (PD-CO, = 10) which received usual care, including participation in conventional physical therapy. Both groups were tested before and after the 8-week AIT program period with the following assessments: (1) laboratory analyses of bimanual motor control, (2) psychological evaluation of cognitive function, and (3) an evaluation of neurological parkinsonian signs.
The PD-TR group exhibited improved (1) bimanual motor control, reflected by a decreased time ( = 0.013) and increased rate of grip force development ( = 0.013) in the manipulating hand and a decreased time delay between grip force initiation in the manipulating and stabilizing hand ( = 0.020); (2) executive function, reflected by decreased performance time in part II of the Stroop Test ( = 0.007); and (3) neurological parkinsonian signs, reflected by an amelioration of upper-extremity bradykinesia ( = 0.015) and improvement in daily life manual functions ( = 0.004), mood, and intellectual function ( = 0.005).
Following an 8-week moderate intensity AIT program, patients with PD exhibited improved psychomotor behaviors, reflected by bimanual motor control, executive function, and neurological parkinsonian signs.
本研究考察了周期性踏车有氧运动间歇训练（AIT）对帕金森病（PD）患者心理运动行为的普遍影响，包括双手运动控制、认知功能以及神经运动和非运动性帕金森氏症体征。
20 名轻至中度 PD 患者被随机分为以下两组：（1）训练组（PD-TR，n=10），除接受常规护理外，还接受 8 周中等强度 AIT 方案；或（2）对照组（PD-CO，n=10），接受常规护理，包括参加常规物理治疗。两组均在 8 周 AIT 方案前后进行以下评估：（1）双手运动控制的实验室分析，（2）认知功能的心理评估，以及（3）神经帕金森氏症体征的评估。
PD-TR 组在以下方面表现出改善：（1）双手运动控制，表现在操纵手上的握力发展时间（ = 0.013）和速率（ = 0.013）降低，以及操纵手和稳定手之间的握力起始时间延迟（ = 0.020）减少；（2）执行功能，表现在 Stroop 测试第二部分的完成时间（ = 0.007）缩短；以及（3）神经帕金森氏症体征，表现在上肢运动迟缓（ = 0.015）改善，日常生活手动功能（ = 0.004）、情绪和智力功能（ = 0.005）提高。
接受 8 周中等强度 AIT 方案后，PD 患者的心理运动行为得到改善，表现在双手运动控制、执行功能和神经运动性帕金森氏症体征。
