Cord Blood Bank, Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud (IDCBIS), Cra. 32 # 12-81, Bogotá, Colombia.
General Direction, Instituto Distrital de Ciencia, Biotecnología e Innovación en Salud (IDCBIS), Cra. 32 # 12-81, Bogotá, Colombia.
Hum Immunol. 2019 Jul;80(7):425-426. doi: 10.1016/j.humimm.2019.03.006. Epub 2019 Mar 9.
Allele and haplotype frequencies were calculated from 1463 umbilical cord blood (UCB) units, from Bogotá (Colombia) donors, HLA-typed in high resolution. This is the first report using allele-level typed colombian samples of five HLA loci related to hematopoietic stem cell transplantation (HLA-A, -B, -C, -DRB1 and -DQB1). The most frequent haplotype found in our sample was A24:02g ∼ B35:43g ∼ C01:02g ∼ DRB104:07g ∼ DQB103:02g (4.14%). Our data are available at the Allele Frequencies Net Database under the code AFND3604.
从哥伦比亚波哥大的 1463 个脐带血 (UCB) 单位中计算出了等位基因和单倍型频率,这些单位经过了高分辨率 HLA 分型。这是首次使用与造血干细胞移植 (HLA-A、-B、-C、-DRB1 和 -DQB1) 相关的五个 HLA 位点进行等位基因水平分型的哥伦比亚样本的报告。在我们的样本中发现的最常见的单倍型是 A24:02gB35:43gC01:02gDRB104:07gDQB103:02g(4.14%)。我们的数据可在 Allele Frequencies Net Database 中以 AFND3604 代码获得。