Department of Internal Medicine, University of Illinois at Chicago - Advocate Christ Medical Center, Oak Lawn, IL 60453, United States.
Department of Gastroenterology, Advocate Christ Medical Center, Oak Lawn, IL 60453, United States.
World J Gastroenterol. 2019 Mar 7;25(9):1080-1087. doi: 10.3748/wjg.v25.i9.1080.
Literature has suggested that imaging is over-utilized in the diagnosis of pancreatitis. If the diagnosis of acute pancreatitis (AP) is established with abdominal pain and increased serum amylase or lipase activity without systemic signs of severe disease, computed tomography (CT) imaging may not be necessary. We hypothesize that among patients with uncomplicated acute pancreatitis (AUP), there is a significant number of unwarranted CT imaging studies. This imposes increased expenditure and cost in our healthcare system and does not improve hospital stay or management of AUP.
To assess the overutilization and associated cost of CT imaging among patients meeting diagnostic criteria for AUP.
In this Institutional Review Board-approved retrospective, single-center study, we identified all adult patients admitted with AP from January 1, 2012 through October 1, 2017. Patients were identified via International Classification of Diseases (ICD-9) code for AP (577.0) and ICD-10 codes for different etiological AP (K85.9 unspecified, K85.0 idiopathic, K85.1 biliary, K85.2 alcohol-induced, K85.3 drug-induced, and K85.8 other). Diagnosis was confirmed by chart review using established non-imaging diagnostic criteria (presence of typical abdominal pain and elevated lipase or amylase greater than 3 times upper limit of normal). Ranson criteria and BISAP scores on presentation were calculated and patients that met scores less than or equal to 2 for both were included to suggest AUP. The utilization and cost of imaging in these patients were recorded.
Between January 2012 and October 2017, 1305 patients presented to the emergency department with AP, and 405 patients (31%) met our inclusion criteria for AUP (201 males, 204 females; mean age 49 years, range 18-98). Of those, 210 patients (51.85%) underwent CT imaging. One patient (0.47%) had evidence of pancreatic necrosis, one patient had cyst formation (0.47%), and the remaining 208 patients (99.05%) had either normal CT scan imaging or findings consistent with mild AP without necrosis. The average cost of CT scan imaging was $4510 with a total cost of $947056. Median length of hospitalization stay was 3 d among both groups. Combining Ranson's Criteria and BISAP score identified AUP in our patient population with an accuracy of 99.5%.
CT imaging is unnecessary when AUP is diagnosed clinically and biochemically. Reducing overuse of diagnostic CT scans will decrease healthcare expenditure and radiation exposure to patients.
文献表明,在胰腺炎的诊断中影像学检查被过度使用。如果急性胰腺炎(AP)的诊断是基于腹痛和血清淀粉酶或脂肪酶活性升高,而没有全身严重疾病的迹象,那么计算机断层扫描(CT)成像可能不是必需的。我们假设,在患有单纯性急性胰腺炎(AUP)的患者中,存在大量不必要的 CT 成像检查。这给我们的医疗系统带来了额外的支出和成本,并不会改善 AUP 的住院时间或管理。
评估符合 AUP 诊断标准的患者中 CT 成像的过度使用情况及其相关成本。
在这项经机构审查委员会批准的回顾性单中心研究中,我们确定了 2012 年 1 月 1 日至 2017 年 10 月 1 日期间因 AP 入院的所有成年患者。通过国际疾病分类(ICD-9)AP 编码(577.0)和 ICD-10 不同病因 AP 编码(K85.9 未特指、K85.0 特发性、K85.1 胆源性、K85.2 酒精性、K85.3 药物性和 K85.8 其他)来识别患者。通过使用既定的非影像学诊断标准(存在典型腹痛和升高的脂肪酶或淀粉酶大于正常值的 3 倍)进行图表审查来确认诊断。计算入院时的 Ranson 标准和 BISAP 评分,并且纳入 Ranson 标准和 BISAP 评分均小于或等于 2 的患者,以提示 AUP。记录这些患者的影像学检查的利用情况和费用。
2012 年 1 月至 2017 年 10 月期间,有 1305 名患者因 AP 就诊于急诊科,其中 405 名(31%)符合我们的 AUP 纳入标准(201 名男性,204 名女性;平均年龄 49 岁,范围 18-98)。其中,210 名患者(51.85%)接受了 CT 成像检查。一名患者(0.47%)有胰腺坏死的证据,一名患者有囊肿形成(0.47%),其余 208 名患者(99.05%)的 CT 扫描结果正常或存在符合无坏死的轻度 AP 的表现。CT 扫描成像的平均费用为 4510 美元,总费用为 947056 美元。两组的中位住院时间均为 3 天。综合 Ranson 标准和 BISAP 评分可在我们的患者人群中准确诊断 AUP,准确率为 99.5%。
当 AUP 在临床和生化上得到诊断时,CT 成像检查是不必要的。减少诊断性 CT 扫描的过度使用将降低医疗保健支出和患者的辐射暴露。