Xiao Yi, Chen Liping, Jing Danrong, Deng Yuxuan, Chen Xiang, Su Juan, Shen Minxue
Department of Dermatology, Xiangya Hospital, Central South University, Changsha, China,
Hunan Engineering Research Center of Skin Health and Disease, Central South University, Changsha, China,
Patient Prefer Adherence. 2019 Feb 22;13:363-370. doi: 10.2147/PPA.S194615. eCollection 2019.
There have been few studies on economic evaluation of acne treatments. Chemical peel (CP), a treatment approach primarily aimed at removing acne hyperpigmentation and scarring, is gradually accepted in the Chinese market.
This study aimed to detect willingness-to-pay (WTP) and to conduct a benefit-cost analysis for CP treatment among Chinese acne patients.
The costs were obtained from the patient's perspective and compared with benefits. The net benefits were approximated by WTP, using the contingent valuation method. A glycolic acid peel served as the demonstrated example. WTP and related information were inquired via an online questionnaire among the Chinese population. Factors for WTP were identified using generalized linear models. The benefit-cost ratio (BCR) was calculated. Discounting was not considered for both WTP and costs.
The response rate of the survey was 95.4% among the 476 anonymous participants. The average cost for three-time CP treatment was USD 383.4. Statistically significant differences in WTP among the cases were identified. The mean WTP for Case 1, Case 2, and Case 3 was USD 234.6, 222.0, and 401.7, respectively. A statistically significant association between WTP and self-reported acne severity was observed for all cases after adjustments for demographic characteristics (<0.01). The Cardiff Acne Disability Index was positively associated with WTP. The BCRs were 0.61, 0.58, and 1.4 for Case 1, Case 2, and Case 3, respectively.
Patients with acne in China are willing to pay for acne treatment. Although the benefits of CP treatment have not generally outweighed their aggregated costs, WTP for CP treatment was positively associated with self-reported acne severity and desirable efficacy of treatment. Individualized acne treatments are recommended to target a specific population in the Chinese market.
关于痤疮治疗的经济学评估研究较少。化学剥脱术(CP)作为一种主要旨在消除痤疮色素沉着和瘢痕的治疗方法,在中国市场正逐渐被接受。
本研究旨在检测中国痤疮患者对化学剥脱术治疗的支付意愿(WTP)并进行效益成本分析。
从患者角度获取成本并与效益进行比较。使用条件价值评估法,通过支付意愿来估算净效益。以乙醇酸剥脱术为例。通过在线问卷在中国人群中询问支付意愿及相关信息。使用广义线性模型确定支付意愿的影响因素。计算效益成本比(BCR)。支付意愿和成本均未考虑贴现。
476名匿名参与者的调查回复率为95.4%。三次化学剥脱术治疗的平均成本为383.4美元。病例之间的支付意愿存在统计学显著差异。病例1、病例2和病例3的平均支付意愿分别为234.6美元、222.0美元和401.7美元。在调整人口统计学特征后,所有病例中支付意愿与自我报告的痤疮严重程度之间均观察到统计学显著关联(<0.01)。卡迪夫痤疮残疾指数与支付意愿呈正相关。病例1、病例2和病例3的效益成本比分别为0.61、0.58和1.4。
中国痤疮患者愿意为痤疮治疗付费。虽然化学剥脱术治疗的效益总体上未超过其总成本,但化学剥脱术治疗的支付意愿与自我报告的痤疮严重程度和理想的治疗效果呈正相关。建议在中国市场针对特定人群进行个体化痤疮治疗。