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痤疮患病率及其与生活方式的关联:7 个欧洲国家青少年/年轻人的横断面在线调查。

Acne prevalence and associations with lifestyle: a cross-sectional online survey of adolescents/young adults in 7 European countries.

机构信息

Department of Dermatology, Hôpital Henri Mondor, APHP, UPEC, Créteil, France.

Department of Dermatology and Venerology, Motol Hospital, Prague, Czech Republic.

出版信息

J Eur Acad Dermatol Venereol. 2018 Feb;32(2):298-306. doi: 10.1111/jdv.14475. Epub 2017 Sep 6.

Abstract

BACKGROUND

Although acne vulgaris is a common skin disorder, limited epidemiological data exist specifically for European populations.

OBJECTIVE

To determine the prevalence of self-reported acne among young people in Europe and evaluate the effect of lifestyle on acne.

METHODS

We conducted a cross-sectional population-based online survey in representative samples of individuals aged 15-24 years in Belgium, Czech and Slovak Republics, France, Italy, Poland and Spain (n = 10 521), identified by a quota sampling method based on age, geographic location and socio-professional category.

RESULTS

The overall adjusted prevalence of self-reported acne was 57.8% (95% confidence interval 56.9% to 58.7%). The rates per country ranged from 42.2% in Poland to 73.5% in the Czech and Slovak Republics. The prevalence of acne was highest at age 15-17 years and decreased with age. On multivariate analysis, a history of maternal or paternal acne was associated with an increased probability of having acne (odds ratio 3.077, 95% CI 2.743 to 3.451, and 2.700, 95% CI 2.391 to 3.049, respectively; both P < 0.0001), as was the consumption of chocolate (OR 1.276, 95% CI 1.094 to 1.488, for quartile 4 vs. quartile 1). Increasing age (OR 0.728, 95% CI 0.639 to 0.830 for age 21-24 years vs. 15-17 years) and smoking tobacco (OR 0.705, 95% CI 0.616 to 0.807) were associated with a reduced probability of acne.

CONCLUSION

The overall prevalence of self-reported acne was high in adolescents/young adults in the European countries investigated. Heredity was the main risk factor for developing acne.

摘要

背景

尽管寻常痤疮是一种常见的皮肤疾病,但针对欧洲人群的特定流行病学数据十分有限。

目的

确定欧洲年轻人中自我报告痤疮的患病率,并评估生活方式对痤疮的影响。

方法

我们通过基于年龄、地理位置和社会职业类别的配额抽样方法,在 15-24 岁的代表性个体中进行了横断面人群在线调查,调查对象来自于比利时、捷克和斯洛伐克共和国、法国、意大利、波兰和西班牙(n=10521)。

结果

总体上,自我报告痤疮的调整后患病率为 57.8%(95%置信区间 56.9%至 58.7%)。每个国家的患病率从波兰的 42.2%到捷克和斯洛伐克共和国的 73.5%不等。痤疮的患病率在 15-17 岁时最高,并随年龄增长而降低。在多变量分析中,母亲或父亲有痤疮史与发生痤疮的概率增加相关(比值比 3.077,95%置信区间 2.743 至 3.451,和 2.700,95%置信区间 2.391 至 3.049;均 P<0.0001),食用巧克力也与痤疮相关(四分位 4 与四分位 1 相比,比值比 1.276,95%置信区间 1.094 至 1.488)。年龄增加(21-24 岁与 15-17 岁相比,比值比 0.728,95%置信区间 0.639 至 0.830)和吸烟(比值比 0.705,95%置信区间 0.616 至 0.807)与痤疮的发生概率降低相关。

结论

在所调查的欧洲国家中,青少年/年轻成年人中自我报告痤疮的总体患病率较高。遗传是发生痤疮的主要危险因素。

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