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亚洲人痤疮及痤疮瘢痕的化学剥脱术:循证综述

Chemical peels for acne and acne scars in asians: evidence based review.

作者信息

Handog Evangeline B, Datuin Maria Suzanne L, Singzon Ivan A

机构信息

Department of Dermatology, Asian Hospital and Medical Center, Muntinlupa, Philippines.

出版信息

J Cutan Aesthet Surg. 2012 Oct;5(4):239-46. doi: 10.4103/0974-2077.104911.

Abstract

Chemical peeling is a widely used procedure in the management of acne and acne scars, but there are very few studies on Asian populations who are more prone to develop hyper pigmentation. This article aims to summarize and evaluate the existing studies on the role of chemical peels in the treatment of acne and acne scars among Asians. An online search was conducted to identify prospective studies published in English that evaluated the use of chemical peels in active acne and acne scars in Asian populations. There were six studies for acne and eight studies for acne scars that were identified using our search parameters. Most were single-centre, open label and with small sample sizes. Acne severity was not uniformly reported and the objective outcome measures of some studies were not explicitly reported as well. The general trend of the results of the studies support the safety and efficacy of chemical peels for acne and acne scars including those of darker skin types. The existing studies support the use of chemical peels in the treatment of acne and acne scars in Asians. Further clinical trials with better study design and more subjects are needed to further establish the role of chemical peels in Asian acne patients.

摘要

化学剥脱术是治疗痤疮及痤疮瘢痕的一种广泛应用的方法,但针对更易出现色素沉着的亚洲人群的研究却非常少。本文旨在总结和评估现有关于化学剥脱术在亚洲人痤疮及痤疮瘢痕治疗中作用的研究。通过在线检索,以识别用英文发表的前瞻性研究,这些研究评估了化学剥脱术在亚洲人群活动性痤疮及痤疮瘢痕治疗中的应用。利用我们的检索参数,共识别出6项关于痤疮的研究和8项关于痤疮瘢痕的研究。大多数研究为单中心、开放标签且样本量较小。痤疮严重程度的报告并不统一,一些研究的客观结局指标也未明确报告。研究结果的总体趋势支持化学剥脱术治疗痤疮及痤疮瘢痕的安全性和有效性,包括对肤色较深的皮肤类型。现有研究支持化学剥脱术用于亚洲人痤疮及痤疮瘢痕的治疗。需要进一步开展设计更好、受试者更多的临床试验,以进一步明确化学剥脱术在亚洲痤疮患者中的作用。

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