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滑石粉胸膜固定术治疗老年持续性漏气继发性气胸

Talc pleurodesis for secondary pneumothorax in elderly patients with persistent air leak.

作者信息

Watanabe Takuya, Fukai Ichiro, Okuda Katsuhiro, Moriyama Satoru, Haneda Hiroshi, Kawano Osamu, Yokota Keisuke, Shitara Masayuki, Tatematsu Tsutomu, Sakane Tadashi, Oda Risa, Nakanishi Ryoichi

机构信息

Department of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.

Department of Thoracic Surgery, Suzuka General Hospital, Suzuka, Japan.

出版信息

J Thorac Dis. 2019 Jan;11(1):171-176. doi: 10.21037/jtd.2018.12.85.

Abstract

BACKGROUND

We herein report the usefulness of two types of talc pleurodesis for secondary pneumothorax of elderly patients with persistent air leak who have severe pulmonary emphysema.

METHODS

We assessed 17 elderly patients with persistent air leak who received talc pleurodesis for secondary pneumothorax from April 2013 to March 2017. Thoracoscopic talc poudrage (TTP) (n=11) was performed in patients whose general condition was thought to sufficiently stable to tolerate for general anesthesia. Talc slurry pleurodesis (TSP) (n=6) via a chest tube was performed in patients whose general condition was thought to be insufficiently stable to tolerate general anesthesia.

RESULTS

The median drainage period after pleurodesis was 6 days in patients who received TTP and 12 days in patients who received TSP. Complications associated with talc pleurodesis included atrial fibrillation (n=1) in the thoracoscopic poudrage group, while the slurry pleurodesis group showed chest pain (n=2), asthmatic attack (n=1), and pneumonia (n=1). All patients who received thoracoscopic poudrage were able to leave the hospital after removal of the chest tube. Five of the six patients who received slurry pleurodesis were able to leave the hospital, but one of them died of acute exacerbation of interstitial pneumonia (IP) on the 45th day after pleurodesis. The success rate was 94% (16/17). There were no cases of recurrence during the observation period.

CONCLUSIONS

TTP was deemed likely to be safe and effective for patients able to tolerate general anesthesia. In patients with IP, especially those treated with steroids, the indication of talc pleurodesis should be cautiously considered.

摘要

背景

我们在此报告两种滑石粉胸膜固定术对患有严重肺气肿且持续性漏气的老年继发性气胸患者的有效性。

方法

我们评估了2013年4月至2017年3月期间接受滑石粉胸膜固定术治疗继发性气胸的17例持续性漏气老年患者。对于一般状况被认为足够稳定以耐受全身麻醉的患者,实施了电视胸腔镜滑石粉喷洒术(TTP)(n = 11)。对于一般状况被认为不够稳定以耐受全身麻醉的患者,通过胸管实施了滑石粉悬液胸膜固定术(TSP)(n = 6)。

结果

接受TTP的患者胸膜固定术后中位引流期为6天,接受TSP的患者为12天。滑石粉胸膜固定术相关的并发症包括电视胸腔镜喷洒术组1例房颤,而悬液胸膜固定术组出现胸痛(n = 2)、哮喘发作(n = 1)和肺炎(n = 1)。所有接受电视胸腔镜喷洒术的患者在拔除胸管后均能出院。接受悬液胸膜固定术的6例患者中有5例能够出院,但其中1例在胸膜固定术后第45天死于间质性肺炎(IP)急性加重。成功率为94%(16/17)。观察期内无复发病例。

结论

对于能够耐受全身麻醉的患者,TTP被认为可能是安全有效的。对于IP患者,尤其是接受类固醇治疗的患者,应谨慎考虑滑石粉胸膜固定术的适应症。

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