Department of Animal Production, College of Food and Agriculture Sciences, King Saud University, Riyadh, Saudi Arabia.
Environ Sci Pollut Res Int. 2019 May;26(14):14194-14199. doi: 10.1007/s11356-019-04615-2. Epub 2019 Mar 12.
The comparative anticoccidial effects of herbal products with a standard synthetic anticoccidial drug on the production performance, intestinal histology, and some blood biochemical parameters in broilers exposed to experimental coccidiosis was investigated. One-day-old broiler chicks (n = 336) were randomly distributed into six groups. One group served as a control, the second was treated with the coccidial infection, the third was treated with synthetic anticoccidial drug (Elancoban), the fourth group was treated with an herbal product (Cozante), the fifth group of birds was treated with Norponin, and the sixth group was treated with Emanox. The results indicated that BWG, BW, FCR, and PEF decreased significantly (P < 0.05) in the positive control. Body weight gain, BW, and PEF were significantly (P < 0.01) high in Elancoban-treated birds. On day 25, lesion score was significantly (P < 0.01) low in duodenum, jejunum, and ceca in Elancoban-treated birds control. On day 30, lesion score was significantly (P < 0.05) low in Emanox-treated birds as compared with the positive control. Albumin concentration was significantly (P < 0.01) low in Emanox while glucose concentration was significantly (P < 0.01) high in all the treated groups compared with the positive control birds. The total antioxidant capacity was significantly (P < 0.05) high in Emanox on day 15 and 30 as compared with the positive control. The results showed that birds exposed to the natural anticoccidial products showed improved villi and total antioxidant capacity. We concluded that herbal products performed better than the positive control group.
本研究旨在探讨在实验性球虫病感染条件下，与标准合成抗球虫药相比，草药产品对生产性能、肠道组织学和一些血液生化参数的比较抗球虫效果。将 1 日龄肉鸡（n=336）随机分为 6 组。一组作为对照组，第二组接受球虫感染，第三组用合成抗球虫药（Elancoban）治疗，第四组用草药（Cozante）治疗，第五组用 Norponin 治疗，第六组用 Emanox 治疗。结果表明，阳性对照组的 BWG、BW、FCR 和 PEF 显著降低（P<0.05）。Elancoban 治疗组的体重增加、BW 和 PEF 显著升高（P<0.01）。第 25 天，十二指肠、空肠和盲肠的病变评分在 Elancoban 治疗组显著降低（P<0.01）。第 30 天，与阳性对照组相比，Emanox 治疗组的病变评分显著降低（P<0.05）。白蛋白浓度在 Emanox 组显著降低（P<0.01），而葡萄糖浓度在所有治疗组均显著升高（P<0.01）与阳性对照组相比。与阳性对照组相比，第 15 天和第 30 天，Emanox 的总抗氧化能力显著升高（P<0.05）。结果表明，暴露于天然抗球虫产品的鸟类显示出改善的绒毛和总抗氧化能力。我们得出结论，草药产品的性能优于阳性对照组。
