Huang Caoxing, Dong Huiling, Su Yan, Wu Yan, Narron Robert, Yong Qiang
Jiangsu Co-Innovation Center for Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.
College of Furnishings and Industrial Design, Nanjing Forestry University, Longpan Road 159, Nanjing 210037, China.
Nanomaterials (Basel). 2019 Mar 7;9(3):387. doi: 10.3390/nano9030387.
The carbon quantum dot (CQD), a fluorescent carbon nanoparticle, has attracted considerable interest due to its photoluminescent property and promising applications in cell imaging and bioimaging. In this work, biocompatible, photostable, and sustainably sourced CQDs were synthesized from byproducts derived from a biorefinery process using one-pot hydrothermal treatment. The main components of byproducts were the degradation products (autohydrolyzate) of biomass pretreated by autohydrolysis. The as-synthesized CQDs had a size distribution from 2.0⁻6.0 nm and had high percentage of sp² and sp³ carbon groups. The CQDs showed blue-green fluorescence with a quantum yield of ~13%, and the fluorescence behaviors were found to be stable with strong resistance to photobleaching and temperature change. In addition, it is found that the as-synthesized CQDs could be used for imaging of cells and tumors, which show potential applications in bioimaging and related fields such as phototherapy and imaging.
碳量子点（CQD）是一种荧光碳纳米颗粒，因其光致发光特性以及在细胞成像和生物成像方面的潜在应用而备受关注。在本工作中，使用一锅水热法从生物炼制过程的副产物中合成了具有生物相容性、光稳定性且来源可持续的CQD。副产物的主要成分是通过自水解预处理的生物质的降解产物（自水解产物）。合成的CQD尺寸分布在2.0⁻6.0纳米之间，且具有高比例的sp²和sp³碳基团。CQD发出蓝绿色荧光，量子产率约为13%，并且发现其荧光行为稳定，具有很强的抗光漂白和抗温度变化能力。此外，发现合成的CQD可用于细胞和肿瘤成像，在生物成像以及光疗和成像等相关领域显示出潜在应用。
