Department of Cardiovascular Medicine, Yale University School of Medicine, New Haven, CT, USA.
Department of Radiology and Biomedical Engineering, Yale University School of Medicine, New Haven, CT, USA.
J Nucl Cardiol. 2020 Aug;27(4):1210-1224. doi: 10.1007/s12350-019-01671-6. Epub 2019 Mar 13.
The complexity of cancer therapies has vastly expanded in the last decade, along with type and severity of cardiac toxicities associated with these treatments. Prevention of pre-clinical cardiotoxicity may improve cardiovascular outcomes and circumvent the decision to place life-sustaining chemotherapeutic agents on hold, making the early detection of cancer therapeutic related cardiac toxicity with non-invasive imaging essential to the care of these patients. There are several established methods of cardiac imaging in the areas of nuclear cardiology, echocardiography, computed tomography, and cardiac magnetic resonance imaging that are used to assess for cardiovascular toxicity of cancer treatments, with several methods under development. The following review will provide an overview of current and emerging imaging techniques in these areas.
在过去的十年中，癌症治疗的复杂性大大增加，同时也伴随着与这些治疗相关的心脏毒性的类型和严重程度。预防临床前的心脏毒性可能会改善心血管结局，并避免因心脏毒性而暂停使用维持生命的化疗药物，因此，早期发现癌症治疗相关的心脏毒性并进行非侵入性成像对于这些患者的治疗至关重要。在核医学、超声心动图、计算机断层扫描和心脏磁共振成像等领域，有几种已确立的心脏成像方法可用于评估癌症治疗的心血管毒性，同时也有几种方法正在开发中。以下综述将介绍这些领域中当前和新兴的成像技术。
