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重度化学性眼烧伤患者的治疗依从性及随访情况

Adherence to Treatment and Follow-Up in Patients with Severe Chemical Eye Burns.

作者信息

Bizrah Mukhtar, Yusuf Ammar, Ahmad Sajjad

机构信息

Imperial College Healthcare NHS Trust, Western Eye Hospital, London, UK.

UCL Institute of Ophthalmology, London, UK.

出版信息

Ophthalmol Ther. 2019 Jun;8(2):251-259. doi: 10.1007/s40123-019-0173-y. Epub 2019 Mar 13.

Abstract

INTRODUCTION

To investigate the demographics, acute management and compliance rates of severe chemical eye burn cases that presented to the largest eye hospital in the United Kingdom (UK).

METHODS

All patients presenting to the Moorfields Eye Hospital emergency department are registered on the electronic patient administration system (PAS). A search of the PAS for patients assigned a preset diagnosis of 'chemical injury' was performed for the period from 1 January to 31 March 2016. The results of the PAS search and handwritten clerking notes were reviewed. Eyes that were found to have ≥ 33% limbal ischaemia or limbal staining, or corneal haze that obscured the details of the iris, were recorded as having severe chemical injuries.

RESULTS

55 patients had mild chemical eye burns, and 11 eyes of 10 patients had severe burns. Average patient age was 37 years (SD 22 years) and 22 years (SD 10 years) for mild and severe chemical injuries, respectively. 53% of the mild injuries and 90% of the severe injuries were in males. 7 (70%) of the 10 severe injuries were assault-related. In the severe chemical injuries group, first presentation to the emergency department was 24 h or more postinjury in 50% of the patients, 33% stopped ascorbate and citrate drops (ocular pain), 40% stopped attending clinical follow-up sessions, and 45% of the eyes had a final best corrected visual acuity (BCVA) of 6/18 or worse.

CONCLUSION

A significant proportion of the severe ocular chemical burns were assault-related. Delayed presentation and poor treatment adherence and follow-up attendance rates are significant challenges in patients with severe chemical burns. Patient education and public health awareness are important strategies. These findings also raise the question of whether these patients, who are mostly young males, should be admitted to improve treatment adherence rates and visual outcome.

摘要

引言

调查就诊于英国最大眼科医院的严重化学性眼烧伤病例的人口统计学特征、急性处理情况及依从率。

方法

所有就诊于摩尔菲尔德眼科医院急诊科的患者均在电子患者管理系统(PAS)中登记。对2016年1月1日至3月31日期间PAS中预设诊断为“化学伤”的患者进行检索。回顾PAS检索结果及手写病历记录。发现角膜缘缺血或染色≥33%,或角膜混浊遮挡虹膜细节的眼睛被记录为有严重化学伤。

结果

55例患者有轻度化学性眼烧伤,10例患者的11只眼睛有严重烧伤。轻度和重度化学伤患者的平均年龄分别为37岁(标准差22岁)和22岁(标准差10岁)。53%的轻度损伤和90%的重度损伤发生在男性。10例严重损伤中有7例(70%)与袭击有关。在严重化学伤组中,50%的患者首次就诊于急诊科是在受伤后24小时或更长时间,33%的患者停止使用抗坏血酸和柠檬酸盐滴眼液(眼痛),40%的患者停止参加临床随访,45%的眼睛最终最佳矫正视力(BCVA)为6/18或更差。

结论

相当一部分严重眼部化学烧伤与袭击有关。就诊延迟、治疗依从性差和随访出勤率低是严重化学烧伤患者面临的重大挑战。患者教育和公众健康意识是重要策略。这些发现还提出了一个问题,即这些大多为年轻男性的患者是否应入院治疗以提高治疗依从率和改善视力预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ea33/6514011/b67804d1a0ad/40123_2019_173_Fig1_HTML.jpg

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