Macdonald E C A, Cauchi P A, Azuara-Blanco A, Foot B
Tennent Institute of Ophthalmology, Gartnavel General Hospital, Great Western Road, Glasgow G12 0YN, UK.
Br J Ophthalmol. 2009 Sep;93(9):1177-80. doi: 10.1136/bjo.2008.154831. Epub 2009 May 4.
To estimate the incidence of severe chemical corneal injuries in the UK and describe presenting clinical features and initial management.
All patients with severe chemical corneal injury in the UK from December 2005 to November 2006 inclusive were prospectively identified using the British Ophthalmological Surveillance Unit. Reporting ophthalmologists provided information regarding presentation and follow-up.
Twelve cases were identified, giving a minimum estimated incidence in the UK of severe chemical corneal injury of 0.02 per 100,000. 66.7% of injuries were in males of working age, 50% occurred at work, and alkali was causative in 66.7%. Only one patient was wearing eye protection at the time of injury, 75% received immediate irrigation. Six patients required one or more surgical procedures, most commonly amniotic membrane graft. At 6 months' follow-up, the best-corrected visual acuity was 6/12 or better in five patients, and worse than 6/60 in two.
The incidence of severe chemical corneal injury in the UK is low. The cases that occur can require extended hospital treatment, with substantial ocular morbidity and visual sequelae. Current enforcement of eye protection in the workplace in the UK has probably contributed to a reduced incidence of severe ocular burns.
评估英国严重化学性角膜损伤的发病率,并描述其呈现的临床特征及初始治疗情况。
通过英国眼科监测单位前瞻性地确定了2005年12月至2006年11月期间英国所有患有严重化学性角膜损伤的患者。报告的眼科医生提供了有关临床表现和随访的信息。
共确定了12例病例,据此估计英国严重化学性角膜损伤的最低发病率为每10万人中0.02例。66.7%的损伤发生在工作年龄的男性中,50%发生在工作时,66.7%由碱引起。受伤时只有1名患者佩戴了眼部防护装置,75%的患者接受了立即冲洗。6名患者需要进行一项或多项手术,最常见的是羊膜移植。在6个月的随访中,5名患者的最佳矫正视力为6/12或更好,2名患者的视力低于6/60。
英国严重化学性角膜损伤的发病率较低。发生的病例可能需要延长住院治疗时间,会出现严重的眼部发病率和视力后遗症。英国目前在工作场所强制要求佩戴眼部防护装置可能有助于降低严重眼部烧伤的发病率。