De Strobel F, Paluš V, Vettorato E, Cherubini G B
North Downs Specialist referrals, Bletchingley, Redhill RH1 4QP, UK.
Veterinary clinic ELPA, Trencin, Slovakia 91195.
J Small Anim Pract. 2019 Jul;60(7):404-410. doi: 10.1111/jsap.12987. Epub 2019 Mar 13.
To describe the prevalence, clinical findings and predictors of disease in dogs with cervical hyperaesthesia.
Medical records of dogs referred for neurological investigation of cervical hyperaesthesia between 2009 and 2013 were retrospectively reviewed. Dogs were assigned to one of the following groups according to the final diagnosis: Non-Neurologic, Brain, Cervical Spine, Multifocal, and Chiari-like Malformation/Syringomyelia. Demographic data, clinical and neurological signs and laboratory findings were compared between groups using univariate analysis; predictors of disease location were assessed by multivariate analysis.
Final diagnostic allocations of the 185 records included in the study were as follows: 2.7% Non-Neurologic, 2.2% Brain, 63.2% Cervical Spine, 22.2% Multifocal and 9.7% Chiari Malformation/Syringomyelia. Intervertebral disc extrusion and steroid-responsive meningitis arteritis were the most common diseases. Compared to Multifocal dogs, those allocated a Cervical Spine diagnosis were older, heavier, more frequently ataxic and lame on a thoracic limb; furthermore, they were less frequently depressed or hyperthermic at presentation. Leucocytosis, neutrophilia and monocytosis were more frequent in dogs allocated a Multifocal diagnosis. Dogs with cervical hyperaesthesia older than 36 months and non-hyperthermic at presentation were more likely to have a lesion of the cervical region rather than a multi-focal disease.
Although non-specific, these results may be useful to guide clinicians in management of dogs presenting with cervical hyperaesthesia. Animal age and body temperature may support the suspicion of either focal or multi-focal cervical spinal disease.
描述患有颈部感觉过敏的犬类疾病的患病率、临床发现及预测因素。
回顾性分析2009年至2013年间因颈部感觉过敏接受神经学检查的犬类病历。根据最终诊断，将犬类分为以下几组：非神经系统疾病组、脑部疾病组、颈椎疾病组、多灶性疾病组以及Chiari样畸形/脊髓空洞症组。使用单因素分析比较各组之间的人口统计学数据、临床和神经学体征以及实验室检查结果；通过多因素分析评估疾病部位的预测因素。
本研究纳入的185份病历的最终诊断分类如下：2.7%为非神经系统疾病，2.2%为脑部疾病，63.2%为颈椎疾病，22.2%为多灶性疾病，9.7%为Chiari畸形/脊髓空洞症。椎间盘突出和类固醇反应性脑膜动脉炎是最常见的疾病。与多灶性疾病的犬相比，被诊断为颈椎疾病的犬年龄更大、体重更重，更常出现共济失调且胸肢跛行；此外，它们就诊时抑郁或体温过高的情况较少见。多灶性疾病诊断的犬白细胞增多、中性粒细胞增多和单核细胞增多更为常见。就诊时年龄大于36个月且体温正常的颈部感觉过敏犬更有可能患有颈部病变而非多灶性疾病。
尽管这些结果不具有特异性，但可能有助于指导临床医生对出现颈部感觉过敏的犬进行管理。动物年龄和体温可能有助于怀疑是局灶性还是多灶性颈椎疾病。
