Chen Hui-Qin, Zhang Rong-Rong, Mei Wen-Li, Cai Cai-Hong, Gai Cui-Juan, Yu Xu-Dong, Dai Hao-Fu
Key Laboratory of Biology and Genetic Resources of Tropical Crops,Ministry of Agriculture,Chinese Academy of Tropical Agricultural Sciences Haikou 571101,China Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine Haikou 571101,China.
Key Laboratory of Biology and Genetic Resources of Tropical Crops,Ministry of Agriculture,Chinese Academy of Tropical Agricultural Sciences Haikou 571101,China Hainan Key Laboratory for Research and Development of Natural Products from Li Folk Medicine Haikou 571101,China College of Agronomy,Hainan University Haikou 570228,China.
Zhongguo Zhong Yao Za Zhi. 2019 Jan;44(1):95-99. doi: 10.19540/j.cnki.cjcmm.20181101.011.
Six compounds were isolated from the aerial part of cultivated Clerodendranthus spicatus in Hainan with various chromatographic techniques,and their structures were determined as:1-dehydroxy-1-oxo-rupestrinol(1),N-trans-feruloyltyramine(2),methyl 3,4-dihydroxyphenyllactate(3),caffein acid(4),methyl caffeate(5) and ethyl caffeate(6),via analysis of physicochemical properties and spectroscopic evidence.Compound 1 was a new compound,while compounds 2 and 3 were isolated from C.spicatus for the first time.Biological activity results showed that compounds 2-4 exhibited α-glucosidase inhibitory activity with different inhibition ratio.
采用多种色谱技术从海南栽培的肾茶地上部分分离得到6个化合物，通过理化性质和光谱数据分析确定它们的结构分别为：1-脱羟基-1-氧代-紫茎女贞醇（1）、N-反式阿魏酰酪胺（2）、3,4-二羟基苯乳酸甲酯（3）、咖啡酸（4）、咖啡酸甲酯（5）和咖啡酸乙酯（6）。化合物1为新化合物，化合物2和3为首次从肾茶中分离得到。生物活性结果表明，化合物2 - 4表现出不同抑制率的α-葡萄糖苷酶抑制活性。
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